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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349531
Species: Homo sapiens
RGD Object: Gene
Symbol: S100A8
Name: S100 calcium binding protein A8
Acc ID: CHEBI:6456
Term: lidocaine
Definition: The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Chemical ID: MESH:D008012
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100A8decreases expressionISOS100a8 (Rattus norvegicus)6480464CTDLidocaine results in decreased expression of S100A8 mRNAPMID:35283115
S100A8increases expressionISOS100a8 (Mus musculus)6480464CTDLidocaine results in increased expression of S100A8 proteinPMID:18382663
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