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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348507
Species: Homo sapiens
RGD Object: Gene
Symbol: FOXP3
Name: forkhead box P3
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FOXP3increases expressionISOFoxp3 (Mus musculus)6480464CTDDextran Sulfate results in increased expression of FOXP3 mRNAPMID:31807802 PMID:34998820
FOXP3increases expressionISOFoxp3 (Rattus norvegicus)6480464CTDDextran Sulfate results in increased expression of FOXP3 mRNAPMID:20881082
FOXP3increases methylationISOFoxp3 (Mus musculus)6480464CTDDextran Sulfate results in increased methylation of FOXP3 genePMID:21858153
FOXP3multiple interactionsISOFoxp3 (Mus musculus)6480464CTDChlorpyrifos inhibits the reaction [Dextran Sulfate results in increased expression of FOXP3 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased methylation of FOXP3 gene]PMID:21858153 PMID:31807802
FOXP3multiple interactionsISOFoxp3 (Rattus norvegicus)6480464CTDkappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of FOXP3 mRNA]PMID:20881082
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