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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346384
Species: Homo sapiens
RGD Object: Gene
Symbol: MPO
Name: myeloperoxidase
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MPOaffects activityISOMpo (Rattus norvegicus)6480464CTDCapsaicin affects the activity of MPO proteinPMID:12893632
MPOdecreases expressionISOMpo (Rattus norvegicus)6480464CTDCapsaicin results in decreased expression of MPO proteinPMID:12024109
MPOmultiple interactionsISOMpo (Rattus norvegicus)6480464CTDCapsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Diquat results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Capsaicin inhibits the reaction [Iodoacetamide results in increased activity of MPO protein]; Capsaicin promotes the reaction [Ethanol results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Capsaicin affects the activity of MPO protein]PMID:10671773 PMID:12893632 PMID:15046732 PMID:15573930
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