GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TNF | increases expression | EXP | | 6480464 | CTD | naringenin metabolite results in increased expression of TNF mRNA | PMID:36235125 | TNF | multiple interactions | EXP | | 6480464 | CTD | [naringenin co-treated with bisphenol A] results in increased expression of TNF mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of TNF mRNA; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein] | PMID:19135038 PMID:36235125 | TNF | decreases activity | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | naringenin results in decreased activity of TNF protein | PMID:22709785 | TNF | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | naringenin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]; naringenin inhibits the reaction [tyloxapol results in increased expression of TNF mRNA] | PMID:18720166 PMID:37076581 | TNF | multiple interactions | ISO | Tnf (Rattus norvegicus) | 6480464 | CTD | naringenin inhibits the reaction [lead acetate results in increased expression of TNF protein]; naringenin inhibits the reaction [TNF protein results in decreased expression of and results in decreased activity of HMOX1 protein]; naringenin inhibits the reaction [TNF protein results in decreased expression of HMOX1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased expression of SPP1 mRNA]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; naringenin inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; zinc protoporphyrin inhibits the reaction [naringenin results in decreased activity of TNF protein] | PMID:22709785 PMID:36807407 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |