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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322206
Species: Mus musculus
RGD Object: Gene
Symbol: Pik3cd
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Acc ID: CHEBI:34631
Term: chlorpyrifos
Definition: An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.
Chemical ID: MESH:D004390
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pik3cdincreases expressionEXP 6480464CTDChlorpyrifos results in increased expression of PIK3CD mRNAPMID:37019170
Pik3cddecreases expressionISOPik3cd (Rattus norvegicus)6480464CTDChlorpyrifos results in decreased expression of PIK3CD mRNAPMID:32905263
Pik3cdincreases methylationISOPik3cd (Rattus norvegicus)6480464CTDChlorpyrifos results in increased methylation of PIK3CD genePMID:32905263
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