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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318374
Species: Homo sapiens
RGD Object: Gene
Symbol: SIRT1
Name: sirtuin 1
Acc ID: CHEBI:72754
Term: bisphenol AF
Definition: An organofluorine compound that is bisphenol A with its methyl hydrogens replaced by fluorines.
Chemical ID: MESH:C583074
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SIRT1decreases expressionISOSirt1 (Rattus norvegicus)6480464CTDbisphenol AF results in decreased expression of SIRT1 proteinPMID:35605789
SIRT1decreases expressionISOSirt1 (Mus musculus)6480464CTDbisphenol AF results in decreased expression of SIRT1 proteinPMID:38043716
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