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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315198
Species: Mus musculus
RGD Object: Gene
Symbol: Dhcr24
Name: 24-dehydrocholesterol reductase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dhcr24decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of DHCR24 mRNAPMID:28213091
Dhcr24increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNAPMID:19770486
Dhcr24multiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to DHCR24 gene]PMID:28213091
Dhcr24decreases expressionISODhcr24 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of DHCR24 mRNAPMID:32109520 PMID:33387578
Dhcr24increases expressionISODhcr24 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNAPMID:21215274
Dhcr24increases expressionISODHCR24 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNAPMID:17555868
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