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GENE - TERM ANNOTATION REPORT

RGD ID: 1311546
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aph1a
Name: aph-1 homolog A, gamma secretase subunit
Acc ID: GO:0030674
Term: protein-macromolecule adaptor activity
Definition: The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
Definition Source(s): GOC:bf, GOC:mah, GOC:vw
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aph1aenablesISOAPH1A (Homo sapiens)1624291RGD PMID:12297508

PMID:12297508
Aph1aenablesIBAPANTHER:PTN000306732 or UniProtKB:Q8WW43 or UniProtKB:Q96BI31600115GO_CentralGO_REF:0000033

GO_REF:0000033
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