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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309114
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf3r
Name: colony stimulating factor 3 receptor
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf3rincreases expressionISOCSF3R (Homo sapiens)6480464CTDTretinoin results in increased expression of CSF3R mRNA; Tretinoin results in increased expression of CSF3R proteinPMID:12441127 PMID:16054129 PMID:29945211 PMID:33167477 PMID:7579340
Csf3rmultiple interactionsISOCSF3R (Homo sapiens)6480464CTD3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]PMID:29945211
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