GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nlrp3 | increases expression | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein | PMID:32968928 PMID:34481870 | Nlrp3 | increases expression | ISO | Nlrp3 (Mus musculus) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA; 1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein | PMID:33994527 | Nlrp3 | multiple interactions | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | ELAVL1 protein affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]]; genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]]; MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]; TLR4 protein inhibits the reaction [genkwanin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]] | PMID:32968928 PMID:34481870 | Nlrp3 | multiple interactions | ISO | Nlrp3 (Mus musculus) | 6480464 | CTD | [1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA]; salvianolic acid B inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein] | PMID:33994527 PMID:38016618 | | ||||||||||||||||||||||
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