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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307751
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding transcription factor 2
Acc ID: CHEBI:69542
Term: (+)-isolariciresinol
Definition: A lignan that is 5,6,7,8-tetrahydronaphthalen-2-ol substituted by hydroxymethyl groups at positions 6 and 7, a methoxy group at position 3 and a 4-hydroxy-3-methoxyphenyl group at position 8. It has been isolated from the roots of Rubia yunnanensis.
Chemical ID: MESH:C060284
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf2decreases expressionISOSREBF2 (Homo sapiens)6480464CTDisolariciresinol results in decreased expression of SREBF2 mRNAPMID:35755389
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