GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Map3k5 | increases expression | ISO | MAP3K5 (Homo sapiens) | 6480464 | CTD | Glucose results in increased expression of MAP3K5 protein | PMID:16731828 | Map3k5 | multiple interactions | ISO | MAP3K5 (Homo sapiens) | 6480464 | CTD | Glucose deficiency promotes the reaction [DAXX protein binds to MAP3K5 protein]; Glucose results in increased phosphorylation of and results in increased activity of MAP3K5 protein | PMID:14505347 PMID:16731828 | Map3k5 | multiple interactions | ISO | Map3k5 (Mus musculus) | 6480464 | CTD | [[[[Glucose results in decreased expression of MIR17 mRNA] which results in increased expression of TXNIP mRNA] which results in increased expression of TXNIP protein] promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; [Glucose promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; Glucose results in increased phosphorylation of and results in increased activity of MAP3K5 protein | PMID:26660634 | | ||||||||||||||||||||||
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