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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305871
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfsf13
Name: TNF superfamily member 13
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf13affects methylationISOTNFSF13 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of TNFSF13 5' UTRPMID:27901495
Tnfsf13decreases expressionISOTnfsf13 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of TNFSF13 mRNAPMID:19770486
Tnfsf13decreases methylationISOTNFSF13 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of TNFSF13 promoterPMID:27901495
Tnfsf13increases expressionISOTNFSF13 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased expression of TNFSF13 mRNAPMID:19152381
Tnfsf13multiple interactionsISOTNFSF13 (Homo sapiens)6480464CTDchlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNFSF13 mRNA]PMID:19152381
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