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GENE - TERM ANNOTATION REPORT

RGD ID: 12349413
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: KRAS
Name: KRAS proto-oncogene, GTPase
Acc ID: DOID:0060578
Term: Noonan syndrome 1
Definition: A Noonan syndrome that has_material_basis_in the PTPN11 gene on chromosome 12q24. (DO)
Definition Source(s): https://www.ncbi.nlm.nih.gov/pubmed/18203203 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KRAS ISOKRAS (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Noonan syndrome 1PMID:16474404 PMID:16474405 PMID:16773572 PMID:17056636 PMID:17551339 PMID:17875937 PMID:18456719 PMID:20949621 PMID:21062266 PMID:21871821 PMID:24033266 PMID:24703799 PMID:25326637 PMID:25741868 PMID:28492532
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