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GENE - TERM ANNOTATION REPORT

RGD ID: 12329024
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: STAT1
Name: signal transducer and activator of transcription 1
Acc ID: GO:0003700
Term: DNA-binding transcription factor activity
Definition: A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
Definition Source(s): GOC:txnOH-2018
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STAT1enablesIEAUniProtKB:P42224 or ensembl:ENSP00000354394150520179Ensembl GO_REF:0000107
STAT1enablesIEAInterPro:IPR001217 or InterPro:IPR008967 or InterPro:IPR022752150520179InterPro GO_REF:0000002
STAT1NOT|enablesISOSTAT1 (Homo sapiens)9068941UniProt PMID:10820245

PMID:10820245
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