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GENE - TERM ANNOTATION REPORT

RGD ID: 12290636
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: TOP2B
Name: DNA topoisomerase II beta
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TOP2Blocated_inIEAUniProtKB:Q02880 or UniProtKB:Q64511 or ensembl:ENSMUSP00000017629 or ensembl:ENSP00000264331150520179Ensembl GO_REF:0000107
TOP2Blocated_inIEAPANTHER:PTHR10169:SF36150520179TreeGrafter GO_REF:0000118
TOP2Blocated_inIEAUniProtKB-KW:KW-0539150520179UniProt GO_REF:0000043
TOP2Blocated_inIEAUniRule:UR000171784150520179UniProt GO_REF:0000104
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