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GENE - TERM ANNOTATION REPORT

RGD ID: 12274185
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: STAT4
Name: signal transducer and activator of transcription 4
Acc ID: GO:0019221
Term: cytokine-mediated signaling pathway
Definition: The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:mah, GOC:signaling, PMID:19295629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
STAT4involved_inIBAMGI:103034 or MGI:103035 or MGI:103036 or MGI:103038 or MGI:103039 or MGI:103062 or MGI:103063 or PANTHER:PTN000210451 or Stat6 (Rattus norvegicus) or UniProtKB:E5F1H4 or UniProtKB:P40763 or UniProtKB:P42224 or UniProtKB:P42226 or UniProtKB:P42229 or UniProtKB:P51692 or UniProtKB:P52630 or UniProtKB:Q14765150520179GO_Central GO_REF:0000033
STAT4acts_upstream_of_or_withinISOStat4 (Mus musculus)9068941MGI PMID:11894097 PMID:12213961

PMID:11894097 PMID:12213961
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