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GENE - TERM ANNOTATION REPORT

RGD ID: 12252074
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: NPPA
Name: natriuretic peptide A
Acc ID: GO:0007168
Term: receptor guanylyl cyclase signaling pathway
Definition: The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.
Definition Source(s): GOC:mah, GOC:signaling, PMID:16815030
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPAinvolved_inIBAPANTHER:PTN002679372 or Nppa (Rattus norvegicus) or UniProtKB:P01160 or UniProtKB:P16860150520179GO_Central GO_REF:0000033
NPPAacts_upstream_of_or_withinISONppa (Rattus norvegicus)9068941MGIPMID:17951249

PMID:17951249 REF_RGD_ID:8553616
NPPAinvolved_inISSUniProtKB:P01160150520179UniProt GO_REF:0000024
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