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GENE - TERM ANNOTATION REPORT

RGD ID: 12220385
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: RYR1
Name: ryanodine receptor 1
Acc ID: DOID:9004616
Term: Left Ventricular Hypertrophy
Definition: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
Definition Source(s): MESH:D017379
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RYR1susceptibilityISORYR1 (Homo sapiens)9068941RGDDAN:SNPs:introns:rs2071090,rs10500279,rs2960321(human)PMID:21828061 REF_RGD_ID:329812015
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