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GENE - TERM ANNOTATION REPORT

RGD ID: 12199151
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: GABBR2
Name: gamma-aminobutyric acid type B receptor subunit 2
Acc ID: GO:0004965
Term: G protein-coupled GABA receptor activity
Definition: Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
Definition Source(s): GOC:ai, GOC:bf, IUPHAR_RECEPTOR:1276, Wikipedia:GABAB_receptor
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GABBR2 ISOGabbr2 (Rattus norvegicus)9068941RGD PMID:11389174 REF_RGD_ID:632824
GABBR2contributes_toIEAUniProtKB:O75899 or ensembl:ENSP00000259455150520179Ensembl GO_REF:0000107
GABBR2enablesIBAFB:FBgn0027575 or FB:FBgn0260446 or PANTHER:PTN000054983 or Gabbr2 (Rattus norvegicus) or Gabbr1 (Rattus norvegicus) or WB:WBGene00021528 or WB:WBGene00022675 or dictyBase:DDB_G0291356150520179GO_Central GO_REF:0000033
GABBR2enablesIEAInterPro:IPR002455 or InterPro:IPR002457150520179InterPro GO_REF:0000002
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