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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11280
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcl12
Name: C-X-C motif chemokine ligand 12
Acc ID: CHEBI:28876
Term: melphalan
Definition: A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Chemical ID: MESH:D008558
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl12decreases expressionISOCXCL12 (Homo sapiens)6480464CTDMelphalan results in decreased expression of CXCL12 mRNA; Melphalan results in decreased expression of CXCL12 proteinPMID:22363485
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