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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11056
Species: Mus musculus
RGD Object: Gene
Symbol: Pam
Name: peptidylglycine alpha-amidating monooxygenase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pamaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PAM mRNAPMID:21570461
Pamaffects expressionISOPam (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of PAM mRNAPMID:34747641
Pamincreases expressionISOPam (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PAM mRNAPMID:32109520
Pamincreases expressionISOPAM (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of PAM mRNAPMID:19619570
Pammultiple interactionsISOPAM (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PAM mRNAPMID:19619570
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