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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11004
Species: Mus musculus
RGD Object: Gene
Symbol: Nppb
Name: natriuretic peptide type B
Acc ID: CHEBI:35457
Term: EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
Definition: An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1).
Chemical ID: MESH:D000806
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppbdecreases expressionISONppb (Rattus norvegicus)6480464CTDAngiotensin-Converting Enzyme Inhibitors results in decreased expression of NPPB mRNAPMID:15667801
Nppbmultiple interactionsISONPPB (Homo sapiens)6480464CTD[Adrenergic beta-Antagonists co-treated with Angiotensin-Converting Enzyme Inhibitors] results in decreased expression of NPPB proteinPMID:21697605
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