GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos3 | decreases response to substance | EXP | | 6480464 | CTD | NOS3 results in decreased susceptibility to sodium arsenite | PMID:16239170 | Nos3 | decreases expression | ISO | Nos3 (Rattus norvegicus) | 6480464 | CTD | sodium arsenite results in decreased expression of NOS3 mRNA | PMID:25058445 PMID:37120063 | Nos3 | increases expression | ISO | Nos3 (Rattus norvegicus) | 6480464 | CTD | sodium arsenite results in increased expression of NOS3 protein | PMID:25218292 | Nos3 | increases expression | ISO | NOS3 (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of NOS3 mRNA; sodium arsenite results in increased expression of NOS3 protein | PMID:12703962 PMID:38568856 | Nos3 | multiple interactions | ISO | Nos3 (Rattus norvegicus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NOS3 protein; Arsenic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NOS3 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of and results in decreased phosphorylation of NOS3 protein]; Atorvastatin inhibits the reaction [sodium arsenite results in decreased expression of NOS3 mRNA]; Atorvastatin inhibits the reaction [sodium arsenite results in increased expression of NOS3 protein]; sodium arsenite results in decreased expression of and results in decreased phosphorylation of NOS3 protein | PMID:25058445 PMID:25218292 PMID:33026618 | | ||||||||||||||||||||||
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