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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10900
Species: Mus musculus
RGD Object: Gene
Symbol: Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kmt2aaffects methylationEXP 6480464CTDbisphenol A affects the methylation of KMT2A promoterPMID:27334623
Kmt2adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of KMT2A mRNAPMID:32156529
Kmt2amultiple interactionsEXP 6480464CTD[bisphenol A co-treated with LIF protein] results in decreased expression of KMT2A mRNAPMID:30951980
Kmt2aaffects expressionISOKmt2a (Rattus norvegicus)6480464CTDbisphenol A affects the expression of KMT2A mRNAPMID:30816183 PMID:35192832
Kmt2adecreases expressionISOKMT2A (Homo sapiens)6480464CTDbisphenol A results in decreased expression of KMT2A mRNAPMID:22576693
Kmt2aincreases expressionISOKmt2a (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of KMT2A mRNAPMID:33441873
Kmt2aincreases methylationISOKMT2A (Homo sapiens)6480464CTDbisphenol A results in increased methylation of KMT2A genePMID:22576693
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