GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il1a | increases expression | ISO | IL1A (Homo sapiens) | 6480464 | CTD | Aspirin results in increased expression of IL1A mRNA | PMID:32816093 | Il1a | multiple interactions | ISO | IL1A (Homo sapiens) | 6480464 | CTD | [Aspirin co-treated with IL1A] results in increased expression of TNF mRNA; Aspirin promotes the reaction [IL1A results in increased expression of CXCL1 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of IL6 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 protein]; Aspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 mRNA]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 protein]; IL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein] | PMID:14742690 | | ||||||||||||||||||||||
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