GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsd11b1 | multiple interactions | EXP | | 6480464 | CTD | Mifepristone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]] | PMID:30993381 | Hsd11b1 | multiple interactions | ISO | Hsd11b1 (Rattus norvegicus) | 6480464 | CTD | [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein] | PMID:22606287 | Hsd11b1 | multiple interactions | ISO | HSD11B1 (Homo sapiens) | 6480464 | CTD | [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]]; Mifepristone affects the reaction [Hydrocortisone affects the expression of HSD11B1 mRNA]; Mifepristone inhibits the reaction [bisphenol A results in increased expression of HSD11B1 mRNA] | PMID:22606287 PMID:23090578 PMID:30528684 | | ||||||||||||||||||||||
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