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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:7726
Term: octreotide
Definition: A homodetic cyclic peptide that has formula C49H66N10O10S2.
Chemical ID: MESH:D015282
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDOctreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased cleavage of CASP3 protein]; SNHG12 mRNA promotes the reaction [Octreotide inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased cleavage of CASP3 protein]]PMID:35307376
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTD[Octreotide results in increased activity of SSTR2 protein] which results in increased activity of CASP3 protein; Octreotide results in increased activity of CASP3 proteinPMID:16601281 PMID:16954443
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