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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10230
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Acc ID: CHEBI:3944
Term: cucurbitacin E
Definition: A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 1, 5 and 23.
Chemical ID: MESH:C102326
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionISOBcl2 (Rattus norvegicus)6480464CTDcucurbitacin E results in decreased expression of BCL2 proteinPMID:27363783
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDcucurbitacin E results in decreased expression of BCL2 proteinPMID:27106530
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