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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10116
Species: Mus musculus
RGD Object: Gene
Symbol: Afp
Name: alpha fetoprotein
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Afpaffects expressionEXP 6480464CTDbisphenol A affects the expression of AFP mRNAPMID:14967926 PMID:30951980
Afpincreases expressionEXP 6480464CTDbisphenol A results in increased expression of AFP mRNA; bisphenol A results in increased expression of AFP proteinPMID:26146954 PMID:34585602
Afpaffects expressionISOAFP (Homo sapiens)6480464CTDbisphenol A affects the expression of AFP mRNAPMID:30903817
Afpdecreases expressionISOAfp (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of AFP mRNAPMID:25181051
Afpincreases expressionISOAfp (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of AFP mRNA; bisphenol A results in increased expression of AFP proteinPMID:32145629
Afpincreases expressionISOAFP (Homo sapiens)6480464CTDbisphenol A results in increased expression of AFP mRNAPMID:27271280
Afpmultiple interactionsISOAFP (Homo sapiens)6480464CTDIGF1 protein affects the reaction [bisphenol A results in increased expression of AFP mRNA]PMID:27271280
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