RGD Annotation Report for leptin system pathwayRat Genome Database

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An association has been curated linking Irs2 and leptin system pathway in Rattus norvegicus.

The association was inferred from sequence orthology (ISO)
The annotation was made from Duan C, etal., J Biol Chem. 2004 Oct 15;279(42):43684-91. Epub 2004 Aug 16.
The annotation has been inferred from sequence orthology with Irs2 (Mus musculus) [(IDA) inferred from direct assay]
11 additional annotations were made from Duan C, etal., J Biol Chem. 2004 Oct 15;279(42):43684-91. Epub 2004 Aug 16.
13 RGD objects have been annotated to leptin system pathway (PW:0000363)
35 papers in RGD have been used to annotate Irs2

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.