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GENE - TERM ANNOTATION REPORT

4 Annotations Found.

An association has been curated linking Ppargc1a and amyotrophic lateral sclerosis in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Thau N, etal., J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.
  • The annotation has been inferred from sequence orthology with Ppargc1a (Mus musculus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Thau N, etal., J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.
  • 397 RGD objects have been annotated to amyotrophic lateral sclerosis  (DOID:332)
  • 175 papers in RGD have been used to annotate Ppargc1a
  • Curation Notes: mRNA:decreased expression:spinal cord, gastrocnemius muscle (mouse)


    • An association has been curated linking Ppargc1a and amyotrophic lateral sclerosis in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Thau N, etal., J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.
  • The annotation has been inferred from sequence orthology with PPARGC1A (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Thau N, etal., J Neuropathol Exp Neurol. 2012 Dec;71(12):1064-74. doi: 10.1097/NEN.0b013e318275df4b.
  • 397 RGD objects have been annotated to amyotrophic lateral sclerosis  (DOID:332)
  • 175 papers in RGD have been used to annotate Ppargc1a
  • Curation Notes: mRNA:decreased expression:motor cortex, muscle (human)


    • An association has been curated linking Ppargc1a and amyotrophic lateral sclerosis in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Liang H, etal., Muscle Nerve. 2011 Dec;44(6):947-56. doi: 10.1002/mus.22217.
  • The annotation has been inferred from sequence orthology with PPARGC1A (Homo sapiens) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Liang H, etal., Muscle Nerve. 2011 Dec;44(6):947-56. doi: 10.1002/mus.22217.
  • 397 RGD objects have been annotated to amyotrophic lateral sclerosis  (DOID:332)
  • 175 papers in RGD have been used to annotate Ppargc1a
  • Curation Notes: human gene in mouse model


    • An association has been curated linking Ppargc1a and amyotrophic lateral sclerosis in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with PPARGC1A (Homo sapiens) [(EXP) inferred from experiment]
  • 397 RGD objects have been annotated to amyotrophic lateral sclerosis  (DOID:332)
  • 175 papers in RGD have been used to annotate Ppargc1a
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:22975021


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