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GENE - TERM ANNOTATION REPORT

6 Annotations Found.

An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Shi SY, etal., J Biol Chem. 2017 Mar 3;292(9):3789-3799. doi: 10.1074/jbc.M116.752519. Epub 2017 Jan 18.
  • The annotation has been inferred from sequence orthology with Jak2 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 89 additional annotations were made from Shi SY, etal., J Biol Chem. 2017 Mar 3;292(9):3789-3799. doi: 10.1074/jbc.M116.752519. Epub 2017 Jan 18.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Qualifier: ameliorates
  • Curation Notes: L-JAK2 KO


    • An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Sonohara F, etal., Oncol Rep. 2015 Feb;33(2):767-73. doi: 10.3892/or.2014.3621. Epub 2014 Nov 25.
  • 2 additional annotations were made from Sonohara F, etal., Oncol Rep. 2015 Feb;33(2):767-73. doi: 10.3892/or.2014.3621. Epub 2014 Nov 25.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Qualifier: severity
  • Curation Notes: mRNA:decreased expression:liver (human)


    • An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Corbit KC, etal., JCI Insight. 2019 Aug 8;5. pii: 131310. doi: 10.1172/jci.insight.131310.
  • The annotation has been inferred from sequence orthology with Jak2 (Mus musculus) [(IMP) inferred from mutant phenotype]
  • 2 additional annotations were made from Corbit KC, etal., JCI Insight. 2019 Aug 8;5. pii: 131310. doi: 10.1172/jci.insight.131310.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Curation Notes: associated with Diseases of the Aged and non-alcoholic fatty liver disease


    • An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Yeh YT, etal., World J Surg. 2012 May;36(5):1128-35. doi: 10.1007/s00268-012-1505-4.
  • The annotation has been inferred from sequence orthology with JAK2 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 11 additional annotations were made from Yeh YT, etal., World J Surg. 2012 May;36(5):1128-35. doi: 10.1007/s00268-012-1505-4.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Qualifier: exacerbates
  • Curation Notes: protein:increased phosphorylation:liver (human)


    • An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
    		•  
  • The annotation was made from Singh AK, etal., Life Sci. 2018 May 15;201:161-172. doi: 10.1016/j.lfs.2018.02.029. Epub 2018 Feb 24.
  • 5 additional annotations were made from Singh AK, etal., Life Sci. 2018 May 15;201:161-172. doi: 10.1016/j.lfs.2018.02.029. Epub 2018 Feb 24.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Qualifier: treatment


    • An association has been curated linking Jak2 and hepatocellular carcinoma in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hou J, etal., Hepatology. 2013 Feb;57(2):678-88. doi: 10.1002/hep.25980. Epub 2012 Oct 30.
  • The annotation has been inferred from sequence orthology with Jak2 (Mus musculus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Hou J, etal., Hepatology. 2013 Feb;57(2):678-88. doi: 10.1002/hep.25980. Epub 2012 Oct 30.
  • 948 RGD objects have been annotated to hepatocellular carcinoma  (DOID:684)
  • 143 papers in RGD have been used to annotate Jak2
  • Curation Notes: protein:increased phosphorylation:liver (mouse)


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