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GENE - TERM ANNOTATION REPORT

14 Annotations Found.

An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Tanizawa Y, etal., Diabetologia. 1993 May;36(5):409-13.
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 3 additional annotations were made from Tanizawa Y, etal., Diabetologia. 1993 May;36(5):409-13.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Qualifier: no_association
  • Curation Notes: DNA:microsatellite marker genotypes:3', 5':no association between genotypes of upstream or downstream microsatellite markers and T2DM in Welsh Caucasians (human)


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Vionnet N, etal., Nature. 1992 Apr 23;356(6371):721-2.
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Vionnet N, etal., Nature. 1992 Apr 23;356(6371):721-2.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: MODY2, OMIM:125851;DNA:point mutation:E279X


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
  •  
  • The annotation was made from Fujimoto Y, etal., Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E414-23. Epub 2004 May 11.
  • 32 additional annotations were made from Fujimoto Y, etal., Am J Physiol Endocrinol Metab. 2004 Sep;287(3):E414-23. Epub 2004 May 11.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: protein:altered localization:hepatocyte:impaired translocation from nucleus to cytoplasm in Zucker diabetic fatty rats


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Noda K, etal., Diabetes. 1993 Aug;42(8):1147-52.
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Noda K, etal., Diabetes. 1993 Aug;42(8):1147-52.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: DNA:polymorphisms::significant association between alleles of two SSLPs and T2DM in a Japanese population (human)


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from Nishi S, etal., Diabet Med. 1994 Mar;11(2):193-7.
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Nishi S, etal., Diabet Med. 1994 Mar;11(2):193-7.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Qualifier: no_association
  • Curation Notes: DNA:polymorphisms:multiple:no association between multiple SSLP and SNP alleles and T2DM in a Japanese population (human)


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from direct assay (IDA)
  •  
  • The annotation was made from Futamura M, etal., Diabetologia. 2012 Apr;55(4):1071-80. doi: 10.1007/s00125-011-2439-3. Epub 2012 Jan 11.
  • 2 additional annotations were made from Futamura M, etal., Diabetologia. 2012 Apr;55(4):1071-80. doi: 10.1007/s00125-011-2439-3. Epub 2012 Jan 11.
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Qualifier: treatment


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from OMIM Disease Annotation Pipeline
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(EXP) inferred from experiment]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:15102714 PMID:15161764 PMID:16123366 PMID:20081858


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: ClinVar Annotator: match by term: Diabetes mellitus, noninsulin-dependent, late onset | ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10426385 PMID:10447526 PMID:10455021 PMID:10525657 PMID:10753050 PMID:11315828 PMID:11372010 PMID:11508276 PMID:11553210 PMID:11942313 PMID:12442280 PMID:12627330 PMID:1360036 PMID:1397713 PMID:14517946 PMID:14517956 PMID:14578306 PMID:1502186 PMID:15305805 PMID:15841481 PMID:15928245 PMID:16059790 PMID:16173921 PMID:16444761 PMID:16602010 PMID:16632067 PMID:16731834 PMID:16965331 PMID:17079173 PMID:17186219 PMID:17389332 PMID:17573900 PMID:17937063 PMID:18271687 PMID:18322640 PMID:18382660 PMID:18399931 PMID:18411240 PMID:19002431 PMID:19309449 PMID:19515026 PMID:19564454 PMID:19790256 PMID:20301620 PMID:20337973 PMID:21104275 PMID:21348868 PMID:21569204 PMID:21604084 PMID:21720051 PMID:21831042 PMID:21921030 PMID:22028181 PMID:22060211 PMID:22335469 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22773699 PMID:22820548 PMID:23275527 PMID:23295287 PMID:23295292 PMID:23771925 PMID:24033266 PMID:24097065 PMID:24323243 PMID:24430320 PMID:24518839 PMID:24568320 PMID:24578721 PMID:24660669 PMID:24735133 PMID:24804978 PMID:24918535 PMID:25015100 PMID:25306193 PMID:25414397 PMID:2555564 PMID:25555642 PMID:25741868 PMID:25850297 PMID:26467025 PMID:26552609 PMID:26587058 PMID:26641800 PMID:27080136 PMID:27185633 PMID:27256595 PMID:27269892 PMID:27271189 PMID:27913849 PMID:28012402 PMID:28170077 PMID:28492532 PMID:28663157 PMID:28701371 PMID:28726111 PMID:29056535 PMID:29207974 PMID:29510678 PMID:29777474 PMID:29927023 PMID:30191644 PMID:30257192 PMID:30259503 PMID:30590153 PMID:30592380 PMID:30656436 PMID:31063852 PMID:31197960 PMID:31216263 PMID:31576961 PMID:31638168 PMID:31957151 PMID:32017842 PMID:32074423 PMID:32375122 PMID:32533152 PMID:32741144 PMID:32792356 PMID:33046911 PMID:33129248 PMID:33477506 PMID:33852230 PMID:34023340 PMID:34393998 PMID:34440516 PMID:34686905 PMID:34746319 PMID:35472491 PMID:36257325 PMID:37008541 PMID:7553875 PMID:8094163 PMID:8094164 PMID:8168652 PMID:8325892 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8495817 PMID:8897004 PMID:9000695 PMID:9049484 PMID:9075802 PMID:9078243 PMID:9435328 PMID:9867845


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10426385 PMID:10447526 PMID:10455021 PMID:10525657 PMID:10753050 PMID:11315828 PMID:11508276 PMID:11942313 PMID:12442280 PMID:12627330 PMID:1360036 PMID:1397713 PMID:14517946 PMID:14517956 PMID:14578306 PMID:15305805 PMID:15841481 PMID:15928245 PMID:16059790 PMID:16173921 PMID:16444761 PMID:16602010 PMID:16632067 PMID:16731834 PMID:16965331 PMID:17079173 PMID:17186219 PMID:17389332 PMID:17573900 PMID:18271687 PMID:18322640 PMID:18382660 PMID:18399931 PMID:18411240 PMID:19002431 PMID:19309449 PMID:19515026 PMID:19790256 PMID:20337973 PMID:21104275 PMID:21348868 PMID:21604084 PMID:21831042 PMID:21921030 PMID:22028181 PMID:22060211 PMID:22335469 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22773699 PMID:22820548 PMID:23295287 PMID:23295292 PMID:24033266 PMID:24097065 PMID:24323243 PMID:24430320 PMID:24518839 PMID:24568320 PMID:24578721 PMID:24660669 PMID:24735133 PMID:24804978 PMID:24918535 PMID:25015100 PMID:25306193 PMID:25414397 PMID:25555642 PMID:25741868 PMID:26467025 PMID:26552609 PMID:27080136 PMID:27185633 PMID:27269892 PMID:27271189 PMID:28012402 PMID:28170077 PMID:28492532 PMID:28663157 PMID:28701371 PMID:28726111 PMID:29056535 PMID:29207974 PMID:29510678 PMID:29777474 PMID:29927023 PMID:30191644 PMID:30257192 PMID:30590153 PMID:30592380 PMID:30656436 PMID:31063852 PMID:31197960 PMID:31216263 PMID:31576961 PMID:31638168 PMID:31957151 PMID:32017842 PMID:32074423 PMID:32375122 PMID:32533152 PMID:32741144 PMID:33046911 PMID:33129248 PMID:33477506 PMID:34023340 PMID:34393998 PMID:34440516 PMID:36257325 PMID:7553875 PMID:8094163 PMID:8094164 PMID:8168652 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8897004 PMID:9000695 PMID:9049484 PMID:9075802 PMID:9078243 PMID:9435328 PMID:9867845


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
  •  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Gck (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: OMIM:125853 | OMIM:601283 | OMIM:601407 | OMIM:603694 | OMIM:608036


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10426385 PMID:10447526 PMID:10455021 PMID:10525657 PMID:10753050 PMID:11315828 PMID:11372010 PMID:11508276 PMID:11553210 PMID:11942313 PMID:12442280 PMID:12627330 PMID:1360036 PMID:1397713 PMID:14517946 PMID:14517956 PMID:14578306 PMID:1502186 PMID:15305805 PMID:15841481 PMID:15928245 PMID:16059790 PMID:16173921 PMID:16444761 PMID:16602010 PMID:16632067 PMID:16731834 PMID:16965331 PMID:17079173 PMID:17186219 PMID:17230658 PMID:17389332 PMID:17573900 PMID:17937063 PMID:18271687 PMID:18322640 PMID:18382660 PMID:18399931 PMID:18411240 PMID:19002431 PMID:19309449 PMID:19515026 PMID:19564454 PMID:19790256 PMID:20301620 PMID:20337973 PMID:21104275 PMID:21348868 PMID:21569204 PMID:21604084 PMID:21720051 PMID:21831042 PMID:21921030 PMID:22028181 PMID:22060211 PMID:22335469 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22773699 PMID:22820548 PMID:23275527 PMID:23295287 PMID:23295292 PMID:23771925 PMID:24033266 PMID:24097065 PMID:24323243 PMID:24430320 PMID:24518839 PMID:24568320 PMID:24578721 PMID:24660669 PMID:24735133 PMID:24804978 PMID:24918535 PMID:25015100 PMID:25306193 PMID:25414397 PMID:2555564 PMID:25555642 PMID:25741868 PMID:25850297 PMID:26467025 PMID:26552609 PMID:26587058 PMID:26641800 PMID:27080136 PMID:27185633 PMID:27256595 PMID:27269892 PMID:27271189 PMID:27913849 PMID:28012402 PMID:28170077 PMID:28492532 PMID:28663157 PMID:28701371 PMID:28726111 PMID:29056535 PMID:29207974 PMID:29510678 PMID:29777474 PMID:29927023 PMID:30191644 PMID:30257192 PMID:30259503 PMID:30590153 PMID:30592380 PMID:30656436 PMID:31063852 PMID:31197960 PMID:31216263 PMID:31576961 PMID:31638168 PMID:31957151 PMID:32017842 PMID:32074423 PMID:32375122 PMID:32533152 PMID:32741144 PMID:32792356 PMID:33046911 PMID:33129248 PMID:33477506 PMID:33852230 PMID:34023340 PMID:34393998 PMID:34440516 PMID:34686905 PMID:34746319 PMID:35472491 PMID:36257325 PMID:36504295 PMID:37008541 PMID:7553875 PMID:8068341 PMID:8094163 PMID:8094164 PMID:8096296 PMID:8168652 PMID:8325892 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8495817 PMID:8897004 PMID:9000695 PMID:9049484 PMID:9075802 PMID:9078243 PMID:9435328 PMID:9867845


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10426385 PMID:10447526 PMID:10455021 PMID:10525657 PMID:10753050 PMID:11315828 PMID:11372010 PMID:11508276 PMID:11942313 PMID:12442280 PMID:12627330 PMID:1360036 PMID:1397713 PMID:14517946 PMID:14517956 PMID:14578306 PMID:1502186 PMID:15305805 PMID:15841481 PMID:15928245 PMID:16059790 PMID:16173921 PMID:16444761 PMID:16602010 PMID:16632067 PMID:16731834 PMID:16965331 PMID:17079173 PMID:17186219 PMID:17389332 PMID:17573900 PMID:17937063 PMID:18271687 PMID:18322640 PMID:18382660 PMID:18399931 PMID:18411240 PMID:19002431 PMID:19309449 PMID:19515026 PMID:19564454 PMID:19790256 PMID:20301620 PMID:20337973 PMID:21104275 PMID:21348868 PMID:21569204 PMID:21604084 PMID:21720051 PMID:21831042 PMID:21921030 PMID:22028181 PMID:22060211 PMID:22335469 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22773699 PMID:22820548 PMID:23275527 PMID:23295287 PMID:23295292 PMID:23771925 PMID:24033266 PMID:24097065 PMID:24323243 PMID:24430320 PMID:24518839 PMID:24568320 PMID:24578721 PMID:24660669 PMID:24735133 PMID:24804978 PMID:24918535 PMID:25015100 PMID:25306193 PMID:25414397 PMID:2555564 PMID:25555642 PMID:25741868 PMID:25850297 PMID:26467025 PMID:26552609 PMID:26587058 PMID:26641800 PMID:27080136 PMID:27185633 PMID:27256595 PMID:27269892 PMID:27271189 PMID:27913849 PMID:28012402 PMID:28170077 PMID:28492532 PMID:28663157 PMID:28701371 PMID:28726111 PMID:29056535 PMID:29207974 PMID:29510678 PMID:29777474 PMID:29927023 PMID:30191644 PMID:30257192 PMID:30259503 PMID:30590153 PMID:30592380 PMID:30656436 PMID:31063852 PMID:31197960 PMID:31216263 PMID:31576961 PMID:31638168 PMID:31957151 PMID:32017842 PMID:32074423 PMID:32375122 PMID:32533152 PMID:32741144 PMID:32792356 PMID:33046911 PMID:33129248 PMID:33477506 PMID:33852230 PMID:34023340 PMID:34393998 PMID:34440516 PMID:34686905 PMID:34746319 PMID:35472491 PMID:36257325 PMID:37008541 PMID:7553875 PMID:8094163 PMID:8094164 PMID:8168652 PMID:8325892 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8495817 PMID:8897004 PMID:9000695 PMID:9049484 PMID:9075802 PMID:9078243 PMID:9435328 PMID:9867845


  • An association has been curated linking Gck and type 2 diabetes mellitus in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
  •  
  • The annotation was made from RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with GCK (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 809 RGD objects have been annotated to type 2 diabetes mellitus  (DOID:9352)
  • 63 papers in RGD have been used to annotate Gck
  • Curation Notes: ClinVar Annotator: match by term: Type 2 diabetes mellitus
  • Original References(s): PMID:10426385 PMID:10447526 PMID:10455021 PMID:10525657 PMID:10753050 PMID:11315828 PMID:11372010 PMID:11508276 PMID:11553210 PMID:11942313 PMID:12442280 PMID:12627330 PMID:1360036 PMID:1397713 PMID:14517946 PMID:14517956 PMID:14578306 PMID:1502186 PMID:15305805 PMID:15841481 PMID:15928245 PMID:16059790 PMID:16173921 PMID:16444761 PMID:16602010 PMID:16632067 PMID:16731834 PMID:16965331 PMID:17079173 PMID:17186219 PMID:17230658 PMID:17389332 PMID:17573900 PMID:17937063 PMID:18271687 PMID:18322640 PMID:18382660 PMID:18399931 PMID:18411240 PMID:19002431 PMID:19309449 PMID:19515026 PMID:19564454 PMID:19790256 PMID:20301620 PMID:20337973 PMID:21104275 PMID:21348868 PMID:21437567 PMID:21569204 PMID:21604084 PMID:21720051 PMID:21831042 PMID:21921030 PMID:22028181 PMID:22060211 PMID:22291974 PMID:22335469 PMID:22389783 PMID:22493702 PMID:22611063 PMID:22761713 PMID:22773699 PMID:22820548 PMID:23275527 PMID:23295287 PMID:23295292 PMID:23771925 PMID:24033266 PMID:24097065 PMID:24323243 PMID:24430320 PMID:24518839 PMID:24568320 PMID:24578721 PMID:24660669 PMID:24735133 PMID:24804978 PMID:24918535 PMID:25015100 PMID:25306193 PMID:25414397 PMID:2555564 PMID:25555642 PMID:25741868 PMID:25850297 PMID:26123671 PMID:26467025 PMID:26552609 PMID:26587058 PMID:26641800 PMID:27080136 PMID:27185633 PMID:27256595 PMID:27269892 PMID:27271189 PMID:27913849 PMID:28012402 PMID:28170077 PMID:28492532 PMID:28663157 PMID:28701371 PMID:28726111 PMID:29056535 PMID:29207974 PMID:29510678 PMID:29777474 PMID:29927023 PMID:30191644 PMID:30257192 PMID:30259503 PMID:30590153 PMID:30592380 PMID:30656436 PMID:31063852 PMID:31197960 PMID:31216263 PMID:31576961 PMID:31638168 PMID:31957151 PMID:32017842 PMID:32041611 PMID:32074423 PMID:32375122 PMID:32533152 PMID:32741144 PMID:32792356 PMID:33046911 PMID:33129248 PMID:33294763 PMID:33477506 PMID:33565752 PMID:33852230 PMID:34023340 PMID:34393998 PMID:34440516 PMID:34686905 PMID:34746319 PMID:35472491 PMID:36178555 PMID:36257325 PMID:36504295 PMID:37008541 PMID:7553875 PMID:8068341 PMID:8094163 PMID:8094164 PMID:8096296 PMID:8168652 PMID:8325892 PMID:8349034 PMID:8433729 PMID:8446612 PMID:8495817 PMID:8897004 PMID:9000695 PMID:9049484 PMID:9075802 PMID:9078243 PMID:9435328 PMID:9867845


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