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GENE - TERM ANNOTATION REPORT

7 Annotations Found.

An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Tang MM, etal., Physiol Behav. 2016 Apr 19. pii: S0031-9384(16)30177-9. doi: 10.1016/j.physbeh.2016.04.034.
  • The annotation has been inferred from sequence orthology with Il6 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Tang MM, etal., Physiol Behav. 2016 Apr 19. pii: S0031-9384(16)30177-9. doi: 10.1016/j.physbeh.2016.04.034.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: protein:increased expression:hippocampus (rat)


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Huang T, etal., Oxid Med Cell Longev. 2019 Jul 15;2019:5813985. doi: 10.1155/2019/5813985. eCollection 2019.
  • 53 additional annotations were made from Huang T, etal., Oxid Med Cell Longev. 2019 Jul 15;2019:5813985. doi: 10.1155/2019/5813985. eCollection 2019.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: protein:increased expression:serum, hippocampus (mouse)


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Huang T, etal., Oxid Med Cell Longev. 2019 Jul 15;2019:5813985. doi: 10.1155/2019/5813985. eCollection 2019.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IEP) inferred from expression pattern]
  • 53 additional annotations were made from Huang T, etal., Oxid Med Cell Longev. 2019 Jul 15;2019:5813985. doi: 10.1155/2019/5813985. eCollection 2019.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: associated with gastric adenocarcinoma; protein:increased expression:blood serum (human)


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Udina M, etal., Psychoneuroendocrinology. 2013 Sep;38(9):1803-13. doi: 10.1016/j.psyneuen.2013.03.007. Epub 2013 Apr 6.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 8 additional annotations were made from Udina M, etal., Psychoneuroendocrinology. 2013 Sep;38(9):1803-13. doi: 10.1016/j.psyneuen.2013.03.007. Epub 2013 Apr 6.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: associated with Chronic Hepatitis C; DNA:insertion/deletion:promoter:


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Zhang L, etal., Dig Dis Sci. 2013 Aug;58(8):2187-96. doi: 10.1007/s10620-013-2656-3. Epub 2013 Apr 16.
  • The annotation has been inferred from sequence orthology with Il6 (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Zhang L, etal., Dig Dis Sci. 2013 Aug;58(8):2187-96. doi: 10.1007/s10620-013-2656-3. Epub 2013 Apr 16.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: mRNA:increased expression:colon


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Frydecka D, etal., Arch Immunol Ther Exp (Warsz). 2016 Dec;64(Suppl 1):169-175. doi: 10.1007/s00005-016-0441-7. Epub 2017 Jan 12.
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(IAGP) inferred by association of genotype and phenotype]
  • 2 additional annotations were made from Frydecka D, etal., Arch Immunol Ther Exp (Warsz). 2016 Dec;64(Suppl 1):169-175. doi: 10.1007/s00005-016-0441-7. Epub 2017 Jan 12.
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Qualifier: treatment
  • Curation Notes: associated with Hepatitis C, Chronic;DNA:SNP:promoter:-174G>C (human)


    • An association has been curated linking Il6 and depressive disorder in Mus musculus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with IL6 (Homo sapiens) [(EXP) inferred from experiment]
  • 188 RGD objects have been annotated to depressive disorder  (DOID:1596)
  • 348 papers in RGD have been used to annotate Il6
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:18458677


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