Phenominer Database Results (254 results)

 
 
How to display a graph
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
F344/NHsd heart right ventricle weight to left ventricle plus septum weight ratio controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 heart right ventricle mass male 105.0 days 23 median 0.41 g/g post excision weight measurement 11569 102
F344/NHsd both adrenal glands wet weight control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 adrenal gland mass male 112.0 days 28 47.0 mg 0.9 4.76 post excision weight measurement 11601 105
F344/NHsd both adrenal glands wet weight control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 adrenal gland mass female 112.0 days 17 51.5 mg 1.9 7.83 post excision weight measurement 11603 105
F344/NHsd heart right ventricle wet weight control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. heart right ventricle mass not specified 84.0 days 23 0.14 g 0.0 0.02 post excision weight measurement 12162 233
F344/NHsd hematocrit control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. erythrocyte quantity female 56.0 days-98.0 days 8 37.6 % 2.76 7.8 automated blood analysis 0.0 Anilytics 13165 332
F344/NHsd left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass female 70.0 days-84.0 days 10 0.55 g 0.02 0.05 digital scale post excision weight measurement 63371 529
F344/NHsd heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass male 70.0 days-84.0 days 10 0.63 g 0.02 0.06 digital scale post excision weight measurement 63434 529
F344/NHsd body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70.0 days-84.0 days 10 29.95 cm 2.66 8.42 in vivo ruler method 63526 529
F344/NHsd body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass male 70.0 days-84.0 days 10 198.7 g 4.49 14.21 whole body digital scale 63608 529
F344/NHsd body weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data body mass female 70.0 days-84.0 days 10 128.5 g 2.13 6.72 whole body digital scale 63617 529
F344/NHsd maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 9 1.0 g/mg 0.07 0.22 wire myography using a Digi-Med tissue force analysis system with force transducer 63158 528
F344/NHsd serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount female 70.0 days-84.0 days 4 149.25 mg/dl 20.01 40.03 standard blood chemistry panel 62482 527
F344/NHsd acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 42.43 % 3.32 8.79 wire myography using a Digi-Med tissue force analysis system with force transducer 62612 528
F344/NHsd acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 54.13 % 6.82 19.3 wire myography using a Digi-Med tissue force analysis system with force transducer 62621 528
F344/NHsd hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70.0 days-84.0 days 7 45.3 % 1.17 3.09 automated blood cell counting method 60649 527
F344/NHsd serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount male 70.0 days-84.0 days 7 1.97 g/dl 0.07 0.18 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 60935 527
F344/NHsd plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait male 70.0 days-84.0 days 7 24.29 mmol/l 1.19 3.15 standard blood chemistry panel 61089 527
F344/NHsd serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 3.8 mmol/l 0.16 0.43 flame atomic emission spectrometry 61315 527
F344/NHsd total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity female 70.0 days-84.0 days 4 4.18 x 1000 cells/ul 0.6 1.2 automated blood cell counting method 61396 527
F344/NHsd serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount female 70.0 days-84.0 days 4 109.75 mmol/l 3.66 7.32 standard blood chemistry panel 62318 527
F344/NHsd blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity female 70.0 days-84.0 days 4 3.36 x 1000 cells/ul 0.65 1.3 automated blood cell counting method 62082 527
F344/NHsd serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount female 70.0 days-84.0 days 4 92.0 U/l 30.56 61.13 standard blood chemistry panel 61468 527
F344/NHsd serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount male 70.0 days-84.0 days 7 8.44 mg/dl 0.32 0.84 standard blood chemistry panel 61551 527
F344/NHsd volume of liver occupied by tumorous lesions as percentage of total liver volume N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 210 days) then partial hepatectomy De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. liver integrity trait not specified  days 12 84.18 % 3.64 12.61 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine 224 days 68353 912
F344/NHsd plasma corticosterone level controlled exposure to ambient light (for 12 hours) Potenza MN, et al., Biol Psychiatry 2004 Mar 15;55(6):634-41. blood corticosterone amount male 49.0 days-59.0 days 9 95.9 ng/ml 16.73 50.19 radioimmunoassay 0.0 68640 970
F344/NHsd serum thyroid stimulating hormone level control condition Baum AE, et al., Endocrinology 2004 Oct 28;. blood thyroid-stimulating hormone amount female 70.0 days- days 15 1.13 ng/ml 0.02 0.07 radioimmunoassay 0.0 serum tsh 67896 252
F344/NHsd red blood cell count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. erythrocyte quantity female 56.0 days-98.0 days 8 0.01 x 10E6 cells/ul 0.0 0.0 automated blood analysis 0.0 Anilytics 68376 332
F344/NHsd inflammatory exudate nitric oxide level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. nitric oxide amount female 56.0 days-98.0 days 10 median 0.12 umol/l liquid phase colorimetry subcutaneous interscapular cavity 0.0 Griess test inflammatory exudate nitric oxide measurement 68404 332
F344/NHsd percentage of study population developing experimental autoimmune neuritis during a period of time peripheral myelin protein 2 peptide 58-81 (100 ug) and Freund's complete adjuvant (100 ul) de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. peripheral nervous system integrity trait male 98.0 days-200.0 days 3 0.0 % ex vivo visual assessment 0.0 peripheral nervous system integrity trait 84526 1178
F344/NHsd body weight fasting (for 16 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 132.0 days-264.0 days 9 375.7 g 8.1 24.3 body weighing method 0.0 84703 1599
F344/NHsd body weight fasting (for 16 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 123.0 days-267.0 days 8 371.3 g 8.3 23.48 body weighing method 0.0 84704 1599
F344/NHsd serum alanine aminotransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alanine transaminase amount male 132.0 days-264.0 days 9 55.0 U/l 3.4 10.2 unspecified method 0.0 84711 1599
F344/NHsd serum alanine aminotransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alanine transaminase amount male 579.0 days-945.0 days 9 54.5 U/l 6.4 19.2 unspecified method 0.0 84713 1599
F344/NHsd serum aspartate aminotransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood aspartate transaminase amount male 714.0 days-882.0 days 5 194.6 U/l 29.1 65.07 unspecified method 0.0 84718 1599
F344/NHsd serum alkaline phosphatase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alkaline phosphatase amount male 123.0 days-267.0 days 7 85.3 U/l 9.9 26.19 unspecified method 0.0 84720 1599
F344/NHsd serum alkaline phosphatase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alkaline phosphatase amount male 579.0 days-945.0 days 9 71.6 U/l 9.4 28.2 unspecified method 0.0 84721 1599
F344/NHsd serum gamma-glutamyltransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood gamma-glutamyltransferase amount male 132.0 days-264.0 days 9 1.2 U/l 0.1 0.3 unspecified method 0.0 84723 1599
F344/NHsd serum gamma-glutamyltransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood gamma-glutamyltransferase amount male 579.0 days-945.0 days 9 2.1 U/l 0.9 2.7 unspecified method 0.0 84725 1599
F344/NHsd serum total protein level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood total protein amount male 132.0 days-264.0 days 9 623.0 g/dl 8.0 24.0 unspecified method 0.0 84727 1599
F344/NHsd serum total bilirubin level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood bilirubin amount male 123.0 days-267.0 days 8 7.6 mg/dl 1.17 3.31 unspecified method 0.0 84736 1599
F344/NHsd serum creatinine level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood creatinine amount male 714.0 days-882.0 days 5 0.74 mg/dl 0.09 0.2 unspecified method 0.0 84742 1599
F344/NHsd bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182.0 days 16 0.22 g/cm2 0.0 0.01 dual-energy x-ray absorptiometry femur 0.0 L3-L5 76294 1578
F344/NHsd serum aspartate aminotransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood aspartate transaminase amount male 132.0 days-264.0 days 9 112.4 U/l 11.3 33.9 unspecified method 0.0 84715 1599
F344/NHsd body weight fasting (for 16 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 579.0 days-945.0 days 9 419.9 g 12.2 36.6 body weighing method 0.0 84705 1599
F344/NHsd volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182.0 days 16 1314.0 mg/cm3 4.0 16.0 ex vivo peripheral quantitative computed tomography diaphysis of femur 0.0 76298 1578
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass male 91.0 days- days 4 386.0 g 8.35 16.7 body weighing method 0.0 body weight 107008 3074
F344/NHsd body weight control condition Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 98.0 days- days 2 224.0 g 0.0 9.2 body weighing method 0.0 body weight 106961 3074
F344/NHsd absolute change in hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (between 0 and 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89.0 days-95.0 days 10 9.0 % 2.3 7.27 microhematocrit tube assay with visual assessment 0.0 initial hematocrit, final hematocrit, change in hematocrit 107268 3077
F344/NHsd water intake drink rate to body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. drinking behavior trait male 89.0 days-95.0 days 10 0.29 ml/d/kg 0.04 0.13 drink intake measuring method arterial catheter implantation 1 days Water consumed (g) postsurgery per 100 g BW 107157 3077
F344/NHsd artery neointimal hyperplastic lesion area balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 0.05 mm2 0.01 0.02 ex vivo light microscopy with digital image analysis 0.0 110473 3107
F344/NHsd artery neointimal hyperplastic lesion area to total wall area ratio balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 30.9 % 2.86 8.58 ex vivo light microscopy with digital image analysis 0.0 110484 3107
F344/NHsd plasma insulin level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood insulin amount female 119.0 days 10 17.0 mU/l 2.4 7.59 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 11615 107
F344/NHsd mean arterial blood pressure control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. arterial blood pressure trait not specified 84.0 days 9 86.0 mmHg 2.0 6.0 vascular indwelling catheter method carotid artery 0.0 pressure transducer (Cobe Laboratories Inc), MacLab 4 integrated data acquisition system (AD Instruments) 12163 233
F344/NHsd plasma corticosterone level control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount male 105.0 days 28 81.0 ng/ml 8.3 43.92 radioimmunoassay 13120 105
F344/NHsd plasma corticosterone level control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount female 105.0 days 17 94.7 ng/ml 21.2 87.41 radioimmunoassay 13122 105
F344/NHsd plasma corticosterone level physical restraint (for 0.2 hours) Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount male 105.0 days 28 354.7 ng/ml 18.9 100.01 radioimmunoassay 0.0 13126 105
F344/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 105.0 days 10 121.7 mg/dl 5.1 16.13 intraperitoneal glucose tolerance test 0 Post glucose injection 60 min 13180 107
F344/NHsd body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length male 70.0 days-84.0 days 10 27.55 cm 2.79 8.81 in vivo ruler method 63680 529
F344/NHsd left kidney wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data kidney mass male 70.0 days-84.0 days 10 0.74 g 0.03 0.09 digital scale post excision weight measurement 63362 529
F344/NHsd body length, nose to rump controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70.0 days-84.0 days 10 26.9 cm 2.32 7.32 in vivo ruler method 63535 529
F344/NHsd body weight controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 body mass male 105.0 days 23 median 238.0 g body weighing method 0 66124 102
F344/NHsd concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 5.39 E-7mole 3.61 9.55 wire myography using a Digi-Med tissue force analysis system with force transducer 63012 528
F344/NHsd hematocrit controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70.0 days-84.0 days 4 46.38 % 2.8 5.61 automated blood cell counting method 60658 527
F344/NHsd mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait male 70.0 days-84.0 days 7 55.36 fl 0.3 0.8 automated blood cell counting method 60761 527
F344/NHsd serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 4.8 mmol/l 0.83 1.65 flame atomic emission spectrometry 61324 527
F344/NHsd serum chloride level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood chloride amount male 70.0 days-84.0 days 7 101.86 mmol/l 1.1 2.91 standard blood chemistry panel 62309 527
F344/NHsd blood lymphocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data lymphocyte quantity male 70.0 days-84.0 days 7 3.77 x 1000 cells/ul 0.62 1.65 automated blood cell counting method 62073 527
F344/NHsd blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity female 70.0 days-84.0 days 4 0.03 x 1000 cells/ul 0.01 0.02 automated blood cell counting method 62236 527
F344/NHsd serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount male 70.0 days-84.0 days 7 22.43 mg/dl 1.29 3.41 standard blood chemistry panel 60167 527
F344/NHsd serum phosphate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood phosphate amount female 70.0 days-84.0 days 4 8.82 mg/dl 1.15 2.3 standard blood chemistry panel 61560 527
F344/NHsd serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount female 70.0 days-84.0 days 4 3.28 g/dl 0.17 0.33 standard blood chemistry panel 61928 527
F344/NHsd liver tumorous lesion number N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 210 days) then partial hepatectomy De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. liver integrity trait not specified  days 12 126820.0 null 9698.0 33594.86 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine 224 days CMO:0001068 68349 912
F344/NHsd blood basophil count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. basophil quantity female 56.0 days-98.0 days 8 0.64 x 1000 cells/ul 0.21 0.6 automated blood analysis blood 0.0 Anilytics 68388 332
F344/NHsd hepatocellular carcinoma tumor number N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 mg/kg) (for 490 days) then partial hepatectomy De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. liver integrity trait not specified  days 9 3.5 null 0.23 0.69 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine 490 days 68391 912
F344/NHsd inflammatory exudate lipoxin A4 level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. eicosanoid amount female 56.0 days-98.0 days 8 median 41.0 pg/ml enzyme linked immunosorbent assay subcutaneous interscapular cavity 0.0 inflammatory exudate LXA4 measurementasurement 68409 332
F344/NHsd number of rearing movements in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. fear-related behavior trait female 77.0 days-88.0 days 18 25.8 null 2.12 9.0 visual assessment of in vivo video recording 600.0 defensive burying number of rearing movements in a defensive burying apparatus (CMO:0004096) 69438 972
F344/NHsd bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. lumbar vertebra mineral mass female 182.0 days 16 0.21 g/cm2 0.0 0.01 dual-energy x-ray absorptiometry lumbar vertebrae 3-5 0.0 L3-L5 76293 1578
F344/NHsd body weight control condition Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 123.0 days-267.0 days 8 379.3 g 9.2 26.02 body weighing method 0.0 84700 1599
F344/NHsd serum alanine aminotransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alanine transaminase amount male 714.0 days-882.0 days 5 51.0 U/l 8.0 17.89 unspecified method 0.0 84714 1599
F344/NHsd serum gamma-glutamyltransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood gamma-glutamyltransferase amount male 714.0 days-882.0 days 5 1.2 U/l 0.2 0.45 unspecified method 0.0 84726 1599
F344/NHsd serum albumin level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood albumin amount male 132.0 days-264.0 days 9 136.0 g/dl 3.0 9.0 unspecified method 0.0 84731 1599
F344/NHsd serum albumin level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood albumin amount male 579.0 days-945.0 days 9 104.0 g/dl 10.0 30.0 unspecified method 0.0 84733 1599
F344/NHsd serum total bilirubin level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood bilirubin amount male 132.0 days-264.0 days 9 5.85 mg/dl 1.17 3.51 unspecified method 0.0 84735 1599
F344/NHsd serum creatinine level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood creatinine amount male 579.0 days-945.0 days 7 0.37 mg/dl 0.05 0.13 unspecified method 0.0 84741 1599
F344/NHsd serum creatinine level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood creatinine amount male 123.0 days-267.0 days 6 0.47 mg/dl 0.02 0.06 unspecified method 0.0 84740 1599
F344/NHsd serum alanine aminotransferase activity level fasting (between 12 and 15 hours) then vehicle control condition (for 1 days) McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. blood alanine transaminase amount not specified 56.0 days-84.0 days 4 35.0 U/l 11.0 22.0 spectrophotometry 0.0 84754 1601
F344/NHsd liver wet weight fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. liver mass male 714.0 days-882.0 days 5 11.8 g 0.9 2.01 post excision weight measurement 0.0 84707 1599
F344/NHsd liver wet weight fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. liver mass male 123.0 days-267.0 days 8 10.0 g 0.4 1.13 post excision weight measurement 0.0 84709 1599
F344/NHsd lactotroph count to total pituicyte count ratio in prolactinoma control condition Pandey J and Wendell DL, Mamm Genome. 2006 Jan;17(1):49-57. Epub 2006 Jan 13. pituitary gland integrity trait female 91.0 days 91.1 % ex vivo light microscopy with immunohistochemistry 0.0 subcutaneous implant 70 days 97078 1838
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 91.0 days- days 4 222.0 g 8.9 17.8 body weighing method 0.0 body weight 107007 3074
F344/NHsd food intake weight to body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. eating behavior trait male 89.0 days-95.0 days 10 4.4 g/d/100g 0.4 1.26 food intake measuring method 0.0 arterial catheter implantation 1 days Food consumed (g) postsurgery per 100 g BW 107141 3077
F344/NHsd hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89.0 days-95.0 days 10 33.0 % 0.7 2.21 microhematocrit tube assay with visual assessment 0.0 initial hematocrit, final hematocrit, change in hematocrit 107252 3077
F344/NHsd body weight 0.9% sodium chloride solution (0.4 ml) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 56.0 days 2 135.0 g 0.0 0.0 body weighing method 0.0 body weight 106983 3074
F344/NHsd nose to rump body mass index control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 14 7.93 (g/cm2) x 10 0.22 0.83 body weighing method 138399 3200
F344/NHsd body weight control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 body mass male 105.0 days 12 median 290.0 g body weighing method 11562 102
F344/NHsd heart left ventricle wet weight controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 heart left ventricle mass male 105.0 days 23 median 0.53 g post excision weight measurement 11568 102
F344/NHsd body weight control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. body mass not specified 84.0 days 23 262.8 g 4.48 21.5 body weighing method 0.0 12133 233
F344/NHsd mean corpuscular hemoglobin concentration control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. blood hemoglobin amount female 56.0 days-98.0 days 8 36.7 g/dl 0.64 1.8 automated blood analysis 0.0 Anilytics 13172 332
F344/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 119.0 days 10 88.0 mg/dl 3.1 9.8 plasma glucose analysis 0 13177 107
F344/NHsd plasma glucose level physical restraint in tube type rodent restrainer (for 0.5 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 105.0 days 10 102.2 mg/dl 4.0 12.65 plasma glucose analysis 0 13179 107
F344/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 119.0 days 10 131.6 mg/dl 3.0 9.49 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 13176 107
F344/NHsd urine calcium excretion rate controlled calcium content diet (0.6 %) (between 4 and 10 days) Hoopes RR Jr, et al., J Am Soc Nephrol 2003 Jul;14(7):1844-50. urine calcium amount male 60.0 days-66.0 days 3 1.72 mg/d 0.14 0.25 urine analysis 86400.0 67507 753
F344/NHsd heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass male 70.0 days-84.0 days 10 0.42 g 0.01 0.04 digital scale post excision weight measurement 63752 529
F344/NHsd heart left ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart left ventricle mass female 70.0 days-84.0 days 10 0.3 g 0.01 0.02 digital scale post excision weight measurement 63761 529
F344/NHsd heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass male 70.0 days-84.0 days 10 0.11 g 0.0 0.01 digital scale post excision weight measurement 63290 529
F344/NHsd heart right ventricle wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart right ventricle mass female 70.0 days-84.0 days 10 0.08 g 0.0 0.01 digital scale post excision weight measurement 63299 529
F344/NHsd heart wet weight controlled sodium content diet (4 %) (for 14 days) PhysGen General data heart mass female 70.0 days-84.0 days 10 0.46 g 0.01 0.03 digital scale post excision weight measurement 63443 529
F344/NHsd mean arterial blood pressure controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 arterial blood pressure trait male 105.0 days 23 median 112.0 mmHg vascular indwelling catheter method left common carotid artery 0 66128 102
F344/NHsd mean arterial blood pressure control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 arterial blood pressure trait male 105.0 days 12 median 121.0 mmHg vascular indwelling catheter method left common carotid artery 0 66127 102
F344/NHsd hematocrit controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 erythrocyte quantity male 105.0 days 23 median 70.0 % hematocrit analysis 0 66132 102
F344/NHsd serum glucose level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood glucose amount male 70.0 days-84.0 days 7 214.43 mg/dl 16.34 43.24 standard blood chemistry panel 62473 527
F344/NHsd concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 9 0.01 umol/l 0.0 0.01 wire myography using a Digi-Med tissue force analysis system with force transducer 62766 528
F344/NHsd logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 7 -6.61 null 0.18 0.49 wire myography using a Digi-Med tissue force analysis system with force transducer 62835 528
F344/NHsd plasma anion gap controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data ion homeostasis trait female 70.0 days-84.0 days 4 28.0 mmol/l 1.96 3.92 standard blood chemistry panel 61098 527
F344/NHsd serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount male 70.0 days-84.0 days 7 5.63 g/dl 0.09 0.23 standard blood chemistry panel 61243 527
F344/NHsd serum total protein level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood total protein amount female 70.0 days-84.0 days 4 5.0 g/dl 0.25 0.5 standard blood chemistry panel 61252 527
F344/NHsd serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount female 70.0 days-84.0 days 4 60.0 mg/dl 7.43 14.85 standard blood chemistry panel 62390 527
F344/NHsd serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 142.57 mmol/l 1.67 4.43 flame atomic emission spectrometry 61797 527
F344/NHsd serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount male 70.0 days-84.0 days 7 0.07 mg/dl 0.01 0.03 standard blood chemistry panel 62145 527
F344/NHsd serum albumin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood albumin amount male 70.0 days-84.0 days 7 3.66 g/dl 0.06 0.17 standard blood chemistry panel 61919 527
F344/NHsd serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount male 70.0 days-84.0 days 7 186.0 U/l 21.39 56.59 standard blood chemistry panel 61991 527
F344/NHsd serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount male 70.0 days-84.0 days 7 221.14 U/l 7.68 20.32 standard blood chemistry panel 60413 527
F344/NHsd serum alkaline phosphatase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alkaline phosphatase amount female 70.0 days-84.0 days 4 142.75 U/l 7.54 15.09 standard blood chemistry panel 60422 527
F344/NHsd mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 7 17.87 pg 0.07 0.19 automated blood cell counting method 60485 527
F344/NHsd mean corpuscular hemoglobin controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 4 18.3 pg 0.07 0.14 automated blood cell counting method 60494 527
F344/NHsd red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity male 70.0 days-84.0 days 7 8.18 x 10E6 cells/ul 0.17 0.46 automated blood cell counting method 60567 527
F344/NHsd red blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte quantity female 70.0 days-84.0 days 4 8.24 x 10E6 cells/ul 0.54 1.08 automated blood cell counting method 60576 527
F344/NHsd percentage of study population developing experimental arthritis during a period of time type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. joint integrity trait female 63.0 days-126.0 days 10 30.0 % in vivo visual assessment 3024000.0 70149 1299
F344/NHsd total white blood cell count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. leukocyte quantity female 56.0 days-98.0 days 8 10.9 x 1000 cells/ul 1.52 4.3 automated blood analysis blood 0.0 Anilytics 68378 332
F344/NHsd total accumulated grooming time in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 28 151.9 s 12.64 66.9 visual assessment of in vivo video recording 600.0 in 10min 68653 972
F344/NHsd percentage of study population developing experimental autoimmune neuritis during a period of time peripheral nerve myelin (2 mg) and Freund's complete adjuvant (100 ul) de Graaf KL, et al., J Neuroimmunol. 2004 Oct;155(1-2):73-84. peripheral nervous system integrity trait male 98.0 days-200.0 days 4 0.0 % ex vivo visual assessment 0.0 peripheral nervous system integrity trait 84476 1178
F344/NHsd serum alkaline phosphatase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alkaline phosphatase amount male 132.0 days-264.0 days 9 98.8 U/l 5.3 15.9 unspecified method 0.0 84719 1599
F344/NHsd serum total protein level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood total protein amount male 579.0 days-945.0 days 9 548.0 g/dl 51.0 153.0 unspecified method 0.0 84729 1599
F344/NHsd serum total protein level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood total protein amount male 123.0 days-267.0 days 8 579.0 g/dl 14.0 39.6 unspecified method 0.0 84728 1599
F344/NHsd serum total bilirubin level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood bilirubin amount male 714.0 days-882.0 days 5 9.35 mg/dl 1.17 2.61 unspecified method 0.0 84738 1599
F344/NHsd serum creatinine level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood creatinine amount male 132.0 days-264.0 days 6 0.38 mg/dl 0.0 0.01 unspecified method 0.0 84739 1599
F344/NHsd total accumulated grooming time in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 20 163.8 s 20.71 92.6 visual assessment of in vivo video recording 600.0 defensive burying apparatus total accumulated grooming time in a defensive burying apparatus (CMO:0004097) 75701 972
F344/NHsd number of rearing movements in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. exploratory behavior trait female 77.0 days-88.0 days 22 28.8 null 2.47 11.6 visual assessment of in vivo video recording 600.0 in 10min 75695 972
F344/NHsd serum aspartate aminotransferase activity level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood aspartate transaminase amount male 579.0 days-945.0 days 6 120.8 U/l 12.9 31.6 unspecified method 0.0 84717 1599
F344/NHsd body weight fasting (for 16 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 714.0 days-882.0 days 5 415.7 g 28.9 64.62 body weighing method 0.0 84706 1599
F344/NHsd volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. femur mineral mass female 182.0 days 16 666.0 mg/cm3 8.0 32.0 ex vivo peripheral quantitative computed tomography distal epiphysis of femur 0.0 76299 1578
F344/NHsd lactotroph count to total pituicyte count ratio in prolactinoma diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J and Wendell DL, Mamm Genome. 2006 Jan;17(1):49-57. Epub 2006 Jan 13. pituitary gland integrity trait female 91.0 days 99.1 % ex vivo light microscopy with immunohistochemistry 0.0 subcutaneous implant 70 days 97077 1838
F344/NHsd percentage of study population developing colorectal tumors during a period of time azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. colorectal integrity trait female 294.0 days- days 8 25.0 % ex vivo light microscopy with immunohistochemistry 0.0 107018 3074
F344/NHsd maximum body weight loss to initial body weight ratio arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. body mass male 89.0 days-95.0 days 10 5.7 % 0.9 2.85 body weighing method 0.0 arterial catheter implantation 1 days 107176 3077
F344/NHsd artery neointimal hyperplastic lesion area including tunica media balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 0.17 mm2 0.03 0.08 ex vivo light microscopy with digital image analysis 0.0 110462 3107
F344/NHsd retroperitoneal fat pad weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. retroperitoneal fat pad mass male 119.0 days 17 5.23 g 0.44 1.8 post excision weight measurement 138401 3200
F344/NHsd mean pulmonary arterial blood pressure control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 pulmonary arterial blood pressure trait male 105.0 days 12 median 16.0 mmHg vascular indwelling catheter method pulmonary artery 0 66123 102
F344/NHsd heart right ventricle wet weight controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 heart right ventricle mass male 105.0 days 23 median 0.21 g post excision weight measurement 11567 102
F344/NHsd plasma insulin level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood insulin amount male 119.0 days 10 43.0 mU/l 4.6 14.55 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 11613 107
F344/NHsd heart wet weight control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. heart mass not specified 84.0 days 23 0.72 g 0.01 0.05 post excision weight measurement 12159 233
F344/NHsd heart left ventricle weight to body weight ratio control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. heart left ventricle mass not specified 84.0 days 23 2.1 mg/g 0.02 0.1 post excision weight measurement 12179 233
F344/NHsd heart left ventricle wet weight control condition Sebkhi A, et al., Hypertension 1999 Apr;33(4):949-53. heart left ventricle mass not specified 84.0 days 23 0.55 g 0.01 0.04 post excision weight measurement 12193 233
F344/NHsd serum thyroid stimulating hormone level control condition Baum AE, et al., Endocrinology 2004 Oct 28;. blood thyroid-stimulating hormone amount male 70.0 days- days 16 2.23 ng/ml 0.16 0.62 radioimmunoassay 0.0 serum tsh 12405 252
F344/NHsd plasma corticosterone level physical restraint (for 0.2 hours) Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount female 105.0 days 17 503.7 ng/ml 32.4 133.59 radioimmunoassay 0 13130 105
F344/NHsd blood hemoglobin level control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. blood hemoglobin amount female 56.0 days-98.0 days 8 13.8 g/dl 0.92 2.6 automated blood cell counting method 0.0 Anilytics 13161 332
F344/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 119.0 days 10 65.1 mg/dl 3.6 11.38 plasma glucose analysis 0 13181 107
F344/NHsd concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 9 0.01 umol/l 0.0 0.01 wire myography using a Digi-Med tissue force analysis system with force transducer 62757 528
F344/NHsd mean corpuscular volume controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data erythrocyte size trait female 70.0 days-84.0 days 4 56.33 fl 0.43 0.86 automated blood cell counting method 60770 527
F344/NHsd blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity female 70.0 days-84.0 days 4 0.79 x 1000 cells/ul 0.36 0.72 automated blood cell counting method 60862 527
F344/NHsd plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount male 70.0 days-84.0 days 7 0.31 mg/dl 0.03 0.07 automated plasma creatinine analysis 61017 527
F344/NHsd mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 7 32.29 g/dl 0.17 0.44 automated blood cell counting method 61161 527
F344/NHsd serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 4 147.25 mmol/l 2.95 5.91 flame atomic emission spectrometry 61806 527
F344/NHsd serum urea nitrogen level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood urea nitrogen amount female 70.0 days-84.0 days 4 32.25 mg/dl 4.61 9.22 standard blood chemistry panel 60176 527
F344/NHsd serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount male 70.0 days-84.0 days 7 20.43 mmol/l 0.75 1.99 standard blood chemistry panel 61623 527
F344/NHsd serum bicarbonate level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bicarbonate amount female 70.0 days-84.0 days 4 14.5 mmol/l 1.5 3.0 standard blood chemistry panel 61632 527
F344/NHsd blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount male 70.0 days-84.0 days 7 14.61 g/dl 0.33 0.88 automated blood cell counting method 60321 527
F344/NHsd serum aspartate aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood aspartate transaminase amount female 70.0 days-84.0 days 4 224.0 U/l 63.85 127.69 standard blood chemistry panel 62000 527
F344/NHsd blood neutrophil count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. neutrophil quantity female 56.0 days-98.0 days 8 2.72 x 1000 cells/ul 0.35 1.0 automated blood analysis heart or retroorbital sinus 0.0 Anilytics 68380 332
F344/NHsd blood lymphocyte count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. lymphocyte quantity female 56.0 days-98.0 days 8 6.75 x 1000 cells/ul 0.92 2.6 automated blood analysis blood 0.0 Anilytics 68382 332
F344/NHsd blood eosinophil count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. eosinophil quantity female 56.0 days-98.0 days 8 0.28 x 1000 cells/ul 0.07 0.2 automated blood analysis blood 0.0 Anilytics 68386 332
F344/NHsd inflammatory exudate leukotriene B4 level to lipoxin A4 level ratio room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. eicosanoid amount female 56.0 days-98.0 days 9 11.4 null enzyme linked immunosorbent assay subcutaneous interscapular cavity 0.0 inflammatory exudate LTB4 to LXA4 ratio 68411 332
F344/NHsd number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 22 13.9 null 1.85 8.7 visual assessment of in vivo video recording 600.0 number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus (CMO:0004098) 75705 972
F344/NHsd number of rearing movements in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. exploratory behavior trait male 77.0 days-88.0 days 28 25.9 null 2.46 13.0 visual assessment of in vivo video recording 600.0 in 10min 75697 972
F344/NHsd body weight control condition Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 132.0 days-264.0 days 5 381.2 g 9.4 21.02 body weighing method 0.0 84708 1599
F344/NHsd serum gamma-glutamyltransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood gamma-glutamyltransferase amount male 123.0 days-267.0 days 8 1.6 U/l 1.0 2.83 unspecified method 0.0 84724 1599
F344/NHsd serum albumin level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood albumin amount male 123.0 days-267.0 days 8 126.0 g/dl 4.0 11.31 unspecified method 0.0 84732 1599
F344/NHsd serum total bilirubin level fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood bilirubin amount male 579.0 days-945.0 days 9 14.62 mg/dl 1.17 3.51 unspecified method 0.0 84737 1599
F344/NHsd percentage of study population developing hepatocellular carcinoma during a period of time N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 490 days) then partial hepatectomy De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. liver integrity trait not specified  days 9 89.0 % necropsy 0.0 N-nitrosodiethylamine 490 days CMO:0001068 96757 912
F344/NHsd serum aspartate aminotransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood aspartate transaminase amount male 123.0 days-267.0 days 7 349.6 U/l 34.3 90.75 unspecified method 0.0 84716 1599
F344/NHsd serum alanine aminotransferase activity level fasting (between 12 and 15 hours) then acetaminophen (1.5 g/kg) (for 1 days) McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. blood alanine transaminase amount not specified 56.0 days-84.0 days 4 101.0 U/l 7.0 14.0 spectrophotometry 0.0 84756 1601
F344/NHsd liver wet weight fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. liver mass male 579.0 days-945.0 days 9 11.7 g 0.4 1.2 post excision weight measurement 0.0 84710 1599
F344/NHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 128.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107332 3077
F344/NHsd body weight control condition Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. body mass male 88.0 days-94.0 days 10 283.0 g 8.0 25.3 body weighing method 0.0 107355 3077
F344/NHsd volume of blood removed to total prehemorrhagic blood volume ratio arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0.4 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. blood amount male 89.0 days-95.0 days 10 5.83 mL/100 g of body weight 57.8 % 0.4 1.26 body weighing method 0.0 volume of blood removed to total prehemorrhagic blood volume ratio (CMO:0003663) 109126 3077
F344/NHsd percentage of study population developing colorectal tumors during a period of time azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. colorectal integrity trait female 217.0 days- days 4 50.0 % ex vivo light microscopy with immunohistochemistry 0.0 107067 3074
F344/NHsd percentage of study population developing colorectal tumors during a period of time azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. colorectal integrity trait male 217.0 days- days 4 100.0 % ex vivo light microscopy with immunohistochemistry 0.0 107068 3074
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 56.0 days 4 140.0 g 6.8 13.6 body weighing method 0.0 body weight 106992 3074
F344/NHsd epididymal fat pad weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. epididymal fat pad mass male 119.0 days 17 7.99 g 0.72 2.98 post excision weight measurement 138402 3200
F344/NHsd heart right ventricle weight to left ventricle plus septum weight ratio control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 heart right ventricle mass male 105.0 days 12 median 0.25 g/g post excision weight measurement 11565 102
F344/NHsd heart left ventricle wet weight control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 heart left ventricle mass male 105.0 days 12 median 0.54 g post excision weight measurement 11564 102
F344/NHsd heart right ventricle wet weight control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 heart right ventricle mass male 105.0 days 12 median 0.14 g post excision weight measurement 11563 102
F344/NHsd mean corpuscular volume control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. erythrocyte size trait female 56.0 days-98.0 days 8 52.0 fl 0.25 0.7 automated blood analysis 0.0 Anilytics 13170 332
F344/NHsd plasma glucose level physical restraint in tube type rodent restrainer (for 0.5 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 105.0 days 10 117.7 mg/dl 2.7 8.54 plasma glucose analysis 0 13178 107
F344/NHsd mean pulmonary arterial blood pressure controlled air oxygen content (10 %) (for 21 days) Zhao L et al., 2001, Circulation, 103(3), 442-7 pulmonary arterial blood pressure trait male 105.0 days 23 median 27.0 mmHg vascular indwelling catheter method pulmonary artery 0 11566 102
F344/NHsd body weight fasting (for 16 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 body mass male 119.0 days 10 345.0 g 5.4 17.08 body weighing method 0 11609 107
F344/NHsd body weight fasting (for 16 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 body mass female 119.0 days 10 221.0 g 3.8 12.02 body weighing method 0 11611 107
F344/NHsd body length, nose to tail controlled sodium content diet (4 %) (for 14 days) PhysGen General data body length female 70.0 days-84.0 days 10 23.85 cm 2.53 7.99 in vivo ruler method 63689 529
F344/NHsd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 9 -8.09 null 0.12 0.36 wire myography using a Digi-Med tissue force analysis system with force transducer EC50 value is moles/liter 63080 528
F344/NHsd logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) PhysGen Vascular data vasoconstriction trait female 70.0 days-84.0 days 9 -8.2 null 0.15 0.45 wire myography using a Digi-Med tissue force analysis system with force transducer EC50 value is moles/liter 63089 528
F344/NHsd maximum contractile force per wet weight of aorta controlled sodium content diet (4 %) (for 14 days) then potassium ion (80 mmol/l) (for 0.2 hours) and phenylephrine (10 umol/l) (for 0.2 hours) PhysGen Vascular data vasoconstriction trait male 70.0 days-84.0 days 8 0.95 g/mg 0.11 0.32 wire myography using a Digi-Med tissue force analysis system with force transducer 63149 528
F344/NHsd hematocrit control condition Zhao L et al., 2001, Circulation, 103(3), 442-7 erythrocyte quantity male 105.0 days 12 median 46.0 % hematocrit analysis 0 66131 102
F344/NHsd urine calcium excretion rate controlled calcium content diet (0.6 %) (between 4 and 10 days) Hoopes RR Jr, et al., J Am Soc Nephrol 2003 Jul;14(7):1844-50. urine calcium amount female 60.0 days-66.0 days 3 1.73 mg/d 0.12 0.21 urine analysis 86400.0 67506 753
F344/NHsd logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 -6.84 null 0.12 0.34 wire myography using a Digi-Med tissue force analysis system with force transducer 62844 528
F344/NHsd body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass male 70.0 days-84.0 days 10 198.7 g 4.49 14.21 whole body digital scale 62923 528
F344/NHsd body weight controlled sodium content diet (4 %) (for 14 days) PhysGen Vascular data body mass female 70.0 days-84.0 days 10 128.3 g 2.14 6.77 whole body digital scale 62932 528
F344/NHsd concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 8 1.9 E-7mole 0.56 1.57 wire myography using a Digi-Med tissue force analysis system with force transducer 63021 528
F344/NHsd blood neutrophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data neutrophil quantity male 70.0 days-84.0 days 7 0.69 x 1000 cells/ul 0.14 0.36 automated blood cell counting method 60853 527
F344/NHsd serum globulin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood globulin amount female 70.0 days-84.0 days 4 1.73 g/dl 0.09 0.17 standard blood chemistry panel replaced obsolete serum globulin level term, 1/19/2016 60944 527
F344/NHsd plasma creatinine level controlled sodium content diet (4 %) (for 14 days) then fasting (between 16 and 1 hours) PhysGen Biochemistry data blood creatinine amount female 70.0 days-84.0 days 4 0.55 mg/dl 0.09 0.17 automated plasma creatinine analysis 61026 527
F344/NHsd mean corpuscular hemoglobin concentration controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 4 32.48 g/dl 0.24 0.48 automated blood cell counting method 61170 527
F344/NHsd total white blood cell count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data leukocyte quantity male 70.0 days-84.0 days 7 4.53 x 1000 cells/ul 0.69 1.82 automated blood cell counting method 61387 527
F344/NHsd serum total cholesterol level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood cholesterol amount male 70.0 days-84.0 days 7 39.14 mg/dl 1.56 4.14 standard blood chemistry panel 62381 527
F344/NHsd blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity male 70.0 days-84.0 days 7 0.05 x 1000 cells/ul 0.02 0.06 automated blood cell counting method 61695 527
F344/NHsd blood monocyte count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data monocyte quantity female 70.0 days-84.0 days 4 0.01 x 1000 cells/ul 0.01 0.02 automated blood cell counting method 61704 527
F344/NHsd serum total bilirubin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood bilirubin amount female 70.0 days-84.0 days 4 0.11 mg/dl 0.03 0.06 standard blood chemistry panel 62154 527
F344/NHsd blood eosinophil count controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data eosinophil quantity male 70.0 days-84.0 days 7 0.03 x 1000 cells/ul 0.02 0.04 automated blood cell counting method 62227 527
F344/NHsd serum alanine aminotransferase activity level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood alanine transaminase amount male 70.0 days-84.0 days 7 73.29 U/l 14.14 37.41 standard blood chemistry panel 61459 527
F344/NHsd serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount male 70.0 days-84.0 days 7 9.64 mg/dl 0.12 0.3 standard blood chemistry panel 60239 527
F344/NHsd serum calcium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood calcium amount female 70.0 days-84.0 days 4 8.55 mg/dl 0.1 0.21 standard blood chemistry panel 60248 527
F344/NHsd blood hemoglobin level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood hemoglobin amount female 70.0 days-84.0 days 4 15.05 g/dl 1.0 1.99 automated blood cell counting method 60330 527
F344/NHsd percentage of study population developing pituitary gland hyperplastic lesions during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91.0 days 6 0.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69912 1240
F344/NHsd percentage of study population developing pituitary tumors that replace the entire gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91.0 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69914 1240
F344/NHsd percentage of study population developing pituitary tumors that invade the glandular capsule during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91.0 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69915 1240
F344/NHsd percentage of study population developing pituitary tumors that replace a portion of the gland during a period of time diethylstilbestrol (5 mg) (for 70 days) and surgical implantation (for 70 days) Pandey J, et al., Carcinogenesis 2004 May 27;. pituitary gland integrity trait not specified 91.0 days 6 50.0 % ex vivo light microscopy 0.0 surgery implant 70 days xco:0000295 69913 1240
F344/NHsd percentage of study population developing experimental arthritis during a period of time type II collagen (2 mg/kg) and Freund's incomplete adjuvant (50 %) Joe B, et al., Immunogenetics 2000 Sep;51(11):930-44. joint integrity trait male 63.0 days-126.0 days 10 20.0 % in vivo visual assessment 3024000.0 70148 1299
F344/NHsd volume of individual liver tumorous lesion N-nitrosodiethylamine (150 mg/kg) then 2-acetamidofluorene (0.02 %) (for 210 days) then partial hepatectomy De Miglio MR, et al., Cancer Res 1999 Sep 15;59(18):4651-7. liver integrity trait not specified  days 12 2.95 cm3 x 10000 0.35 312.98 ex vivo light microscopy with digital image analysis 0.0 N-nitrosodiethylamine 224 days 68351 912
F344/NHsd blood monocyte count control condition Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. monocyte quantity female 56.0 days-98.0 days 8 0.51 x 1000 cells/ul 0.14 0.4 automated blood analysis blood 0.0 Anilytics 68384 332
F344/NHsd inflammatory exudate neutrophil count room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. neutrophil quantity female 56.0 days-98.0 days 14 23.2 x 10E6 cells/ml 2.4 8.98 hemocytometer subcutaneous interscapular cavity 0.0 hemocytometer 68394 332
F344/NHsd inflammatory exudate mononuclear leukocyte count room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. leukocyte quantity female 56.0 days-98.0 days 14 3.8 x 10E6 cells/ml 0.4 1.5 hemocytometer subcutaneous interscapular cavity 0.0 hemocytometer inflammatory air pouch exudate mononuclear cell count 68396 332
F344/NHsd inflammatory exudate tumor necrosis factor level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. tumor necrosis factor amount female 56.0 days-98.0 days 9 809.0 pg/ml 143.0 429.0 enzyme linked immunosorbent assay subcutaneous interscapular cavity 0.0 hemocytometer inflammatory air pouch exudate Tnf level 68400 332
F344/NHsd inflammatory exudate leukotriene B4 level room temperature (14 ml) (for 3 days) then room temperature (10 ml) (for 3 days) then carrageenan (1 ml) (for 6 hours) Laragione T, et al., J Immunol. 2007 Feb 15;178(4):2344-51. eicosanoid amount female 56.0 days-98.0 days 9 median 469.0 pg/ml enzyme linked immunosorbent assay subcutaneous interscapular cavity 0.0 inflammatory exudate LTB4 measurement 68407 332
F344/NHsd total accumulated grooming time in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 22 178.5 s 18.83 88.3 visual assessment of in vivo video recording 600.0 in 10min 68651 972
F344/NHsd number of rearing movements in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. fear-related behavior trait male 77.0 days-88.0 days 20 21.7 null 2.28 10.2 visual assessment of in vivo video recording 600.0 defensive burying apparatus number of rearing movements in a defensive burying apparatus (CMO:0004096) 75693 972
F344/NHsd liver wet weight fasting (for 16 hours) then sodium chloride solution (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. liver mass male 132.0 days-264.0 days 9 10.9 g 0.4 1.2 post excision weight measurement 0.0 84699 1599
F344/NHsd body weight control condition Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 579.0 days-945.0 days 9 424.8 g 14.5 43.5 body weighing method 0.0 84701 1599
F344/NHsd body weight control condition Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. body mass male 714.0 days-882.0 days 5 429.1 g 30.0 67.08 body weighing method 0.0 84702 1599
F344/NHsd serum alkaline phosphatase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alkaline phosphatase amount male 714.0 days-882.0 days 5 48.2 U/l 5.8 12.97 unspecified method 0.0 84722 1599
F344/NHsd serum albumin level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood albumin amount male 714.0 days-882.0 days 5 108.0 g/dl 9.0 20.12 unspecified method 0.0 84734 1599
F344/NHsd total accumulated grooming time in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 18 152.0 s 22.82 96.8 visual assessment of in vivo video recording 600.0 defensive burying apparatus total accumulated grooming time in a defensive burying apparatus (CMO:0004097) 75699 972
F344/NHsd number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 28 10.2 null 1.32 7.0 visual assessment of in vivo video recording 600.0 number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus (CMO:0004098) 75703 972
F344/NHsd serum alanine aminotransferase activity level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood alanine transaminase amount male 123.0 days-267.0 days 8 109.3 U/l 14.3 40.45 unspecified method 0.0 84712 1599
F344/NHsd serum total protein level fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. blood total protein amount male 714.0 days-882.0 days 5 592.0 g/dl 13.0 29.07 unspecified method 0.0 84730 1599
F344/NHsd serum alanine aminotransferase activity level fasting (between 12 and 15 hours) then acetaminophen (1 g/kg) (for 1 days) McGill MR, et al., Toxicol Appl Pharmacol. 2012 Nov 1;264(3):387-94. doi: 10.1016/j.taap.2012.08.015. Epub 2012 Aug 23. blood alanine transaminase amount not specified 56.0 days-84.0 days 4 39.0 U/l 4.0 8.0 spectrophotometry 0.0 84755 1601
F344/NHsd volumetric bone mineral density control condition Koller DL, et al., Mamm Genome 2005 Aug;16(8):578-86. Epub 2005 Sep 14. lumbar vertebra mineral mass female 182.0 days 16 684.0 mg/cm3 6.0 24.0 ex vivo peripheral quantitative computed tomography lumbar vertebrae 3-5 0.0 L3-L5 76297 1578
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 98.0 days- days 8 224.0 g 3.11 8.8 body weighing method 0.0 body weight 107004 3074
F344/NHsd body weight control condition Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 63.0 days 2 152.0 g 0.0 5.7 body weighing method 0.0 body weight 106960 3074
F344/NHsd body weight 0.9% sodium chloride solution (1 ml) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 91.0 days- days 2 232.0 g 4.53 6.4 body weighing method 0.0 body weight 107013 3074
F344/NHsd body weight 0.9% sodium chloride solution (1 ml) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass male 91.0 days- days 2 417.0 g 17.47 24.7 body weighing method 0.0 body weight 107014 3074
F344/NHsd hematocrit arterial catheter implantation (for 1 days) then controlled hemorrhage (for 0 hours) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. erythrocyte quantity male 89.0 days-95.0 days 10 42.0 % 2.1 6.64 microhematocrit tube assay with visual assessment 0.0 initial hematocrit, final hematocrit, change in hematocrit 107235 3077
F344/NHsd body weight 0.9% sodium chloride solution (0.4 ml) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass male 56.0 days 2 200.0 g 6.01 8.5 body weighing method 0.0 body weight 106984 3074
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass female 63.0 days 8 161.0 g 2.37 6.7 body weighing method 0.0 body weight 106988 3074
F344/NHsd body weight azoxymethane (15 mg/kg) Kobaek-Larsen M, etal., Comp Med. 2002 Feb;52(1):50-7. body mass male 56.0 days 4 197.0 g 5.15 10.3 body weighing method 0.0 body weight 106993 3074
F344/NHsd body weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 17 345.0 g 11.63 47.95 body weighing method 138398 3200
F344/NHsd nose to tail body mass index control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 14 2.17 (g/cm2) x 10 0.05 0.2 body weighing method 138400 3200