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glyburide pharmacodynamics pathway - Ontology Report - Rat Genome Database

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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:glyburide pharmacodynamics pathway
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Accession:PW:0002011 term browser browse the term
Definition:The pathway of glyburide-target interaction and of the biochemical or physiological responses to drug. The drug is used in the treatment of type 2 diabetes mellitus. Glyburide is also known as glibenclamide. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00460;   glibenclamide pharmacodynamics pathway

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glyburide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO SMPDB SMP:00460 NCBI chrNW_004936528:1,608,782...1,682,873
Ensembl chrNW_004936528:1,608,757...1,682,975 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00460 NCBI chrNW_004936529:1,889,811...2,023,710
Ensembl chrNW_004936529:1,889,846...2,023,715 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00460 NCBI chrNW_004936490:14,448,305...14,468,785
Ensembl chrNW_004936490:14,448,258...14,468,785 		JBrowse link
G Ins insulin ISO SMPDB SMP:00460 NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357 		JBrowse link
G LOC101960999 voltage-dependent P/Q-type calcium channel subunit alpha-1A ISO SMPDB SMP:00460 NCBI chrNW_004936659:2,201,606...2,269,625
Ensembl chrNW_004936659:2,192,610...2,392,638 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO SMPDB SMP:00460 NCBI chrNW_004936593:1,572,661...1,605,071
Ensembl chrNW_004936593:1,572,672...1,604,947 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 3945
    drug pathway 362
      alimentary tract and metabolism drug pathway 70
        anti-diabetic drug pathway 10
          glyburide drug pathway 6
            glyburide pharmacodynamics pathway 6
paths to the root