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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal spleen marginal zone morphology
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Accession:MP:0002362 term browser browse the term
Definition:any structural anomaly of the zone between the red and white pulp of the spleen containing numerous macrophages and lymphocytes, and a rich plexus of sinusoids supplied by white pulp arterioles carrying blood-borne antigens
Comment:Note that there is no consensus in the literature about which compartments constitute the white pulp or the ramifications of the microvasculature. In addition, notable differences exist between humans and rodents. In this ontology, the marginal zone has been included as part of the white pulp.
Synonyms:exact_synonym: abnormal splenic marginal zone morphology

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Path 1
Term Annotations click to browse term
  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal spleen morphology 0
          abnormal spleen white pulp morphology 0
            abnormal spleen marginal zone morphology 0
              abnormal marginal zone B cell morphology + 0
              abnormal spleen marginal zone macrophage morphology 0
              absent spleen marginal zone 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 0
    immune system phenotype 0
      abnormal immune system morphology 0
        abnormal immune system organ morphology 0
          abnormal spleen morphology 0
            abnormal spleen white pulp morphology 0
              abnormal spleen marginal zone morphology 0
                abnormal marginal zone B cell morphology + 0
                abnormal spleen marginal zone macrophage morphology 0
                absent spleen marginal zone 0
paths to the root