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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal spleen marginal zone macrophage morphology
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Accession:MP:0008240 term browser browse the term
Definition:any structural anomaly of the cells present in the splenic marginal zone and are involved in the recognition and clearance of material, such as pathogen-derived material, from the splenic circulation
Comment:Spleen marginal zone macrophage cells express the cell surface protein CD209b (also called Signr1), which is often detected with the ER-TR9 antibody.
Synonyms:exact_synonym: abnormal ER-TR9 positive cells;   abnormal splenic marginal zone macrophage morphology


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Term Annotations click to browse term
  mammalian phenotype 5402
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal spleen morphology 33
          abnormal spleen white pulp morphology 3
            abnormal spleen marginal zone morphology 0
              abnormal spleen marginal zone macrophage morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal leukocyte morphology 154
            abnormal myeloid leukocyte morphology 70
              abnormal phagocyte morphology 47
                abnormal mononuclear phagocyte morphology 42
                  abnormal macrophage morphology 36
                    abnormal spleen marginal zone macrophage morphology 0
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