Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:very long-chain fatty acid beta-oxidation
go back to main search page
Accession:GO:0140493 term browser browse the term
Definition:A fatty acid beta-oxidation pathway acting on a very long-chain fatty acid. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons. The partway stars with the conversion of an acyl-CoA to a trans-2-enoyl-CoA, catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
Comment:While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
very long-chain fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:1,115,607...1,140,085
Ensembl chrNW_004936594:1,112,565...1,140,228 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15971
    metabolic process 9633
      cellular metabolic process 7988
        cellular lipid metabolic process 962
          cellular lipid catabolic process 219
            fatty acid catabolic process 100
              very long-chain fatty acid catabolic process 7
                very long-chain fatty acid beta-oxidation 1
Path 2
Term Annotations click to browse term
  biological_process 15971
    metabolic process 9633
      cellular metabolic process 7988
        organic acid metabolic process 879
          oxoacid metabolic process 862
            carboxylic acid metabolic process 848
              monocarboxylic acid metabolic process 594
                fatty acid metabolic process 379
                  fatty acid catabolic process 100
                    fatty acid beta-oxidation 74
                      fatty acid beta-oxidation using acyl-CoA oxidase 4
                        very long-chain fatty acid beta-oxidation 1
paths to the root