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ONTOLOGY REPORT - ANNOTATIONS

Term:receptor antagonist activity
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Accession:GO:0048019 term browser browse the term
Definition:The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
Synonyms:broad_synonym: receptor ligand activity


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receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide enables ISO (PMID:9600267) UniProt PMID:9600267 NCBI chr 4:91,833,111...91,856,325
Ensembl chr 4:102,494,784...102,518,215 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776 		JBrowse link
G DKK2 dickkopf WNT signaling pathway inhibitor 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:99,428,210...99,542,884
Ensembl chr 4:110,001,499...110,117,326 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G DKK4 dickkopf WNT signaling pathway inhibitor 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 8:41,618,173...41,638,550
Ensembl chr 8:39,062,711...39,082,575 		JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:3,663,649...3,683,450
Ensembl chr 4:3,646,179...3,666,098 		JBrowse link
G MTRNR2L11 MT-RNR2 like 11 enables IEA TreeGrafter GO_REF:0000118 Ensembl chr 1:218,495,474...218,495,548 JBrowse link
G MTRNR2L13 MT-RNR2 like 13 enables IEA TreeGrafter GO_REF:0000118 Ensembl chr 4:119,346,741...119,346,815 JBrowse link
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 enables ISO (PMID:21054789) UniProt PMID:21054789
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569 		JBrowse link
activin receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FST follistatin enables ISO (PMID:12702211) UniProt PMID:12702211 NCBI chr 5:60,544,495...60,550,516 JBrowse link
G IGSF1 immunoglobulin superfamily member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr  X:120,406,725...120,422,636
Ensembl chr  X:130,714,061...130,729,963 		JBrowse link
chemokine receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL5 C-C motif chemokine ligand 5 enables IEA Ensembl GO_REF:0000107 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
interleukin-1 receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
interleukin-1 type I receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables IEA Ensembl GO_REF:0000107 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
interleukin-1 type II receptor antagonist activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist enables IEA Ensembl GO_REF:0000107 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17493
    binding 16142
      protein binding 14561
        signaling receptor binding 1468
          receptor antagonist activity 14
            activin receptor antagonist activity 2
            chemokine receptor antagonist activity 1
            fibroblast growth factor receptor antagonist activity 0
            interleukin-1 receptor antagonist activity + 1
paths to the root