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ONTOLOGY REPORT - ANNOTATIONS


Term:ketone body biosynthetic process
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Accession:GO:0046951 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
Synonyms:exact_synonym: ketone body anabolism;   ketone body biosynthesis;   ketone body formation;   ketone body synthesis


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ketone body biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase JBrowse link 5 154,294,841 154,308,582 RGD:1599519
RGD:13792537
RGD:1624291
G Hmgcll1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 JBrowse link 8 83,069,837 83,204,778 RGD:1600115
RGD:1624291
RGD:13792537
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:728598
RGD:1624291
RGD:2326121
G Slc27a5 solute carrier family 27 member 5 JBrowse link 1 65,576,599 65,587,192 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19576
    metabolic process 11899
      biosynthetic process 5967
        cellular biosynthetic process 5791
          ketone body biosynthetic process 4
            acetoacetic acid biosynthetic process 0
            acetone biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19576
    cellular process 18361
      cellular metabolic process 10737
        drug metabolic process 591
          ketone body metabolic process 10
            ketone body biosynthetic process 4
              acetoacetic acid biosynthetic process 0
              acetone biosynthetic process 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.