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ONTOLOGY REPORT - ANNOTATIONS
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Term:
UDP-N-acetylglucosamine 2-epimerase activity
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Accession:
GO:0008761
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Definition:
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
Synonyms:
related_synonym:
UDP-GlcNAc-2-epimerase activity; UDP-N-acetyl-D-glucosamine 2-epimerase activity; uridine diphosphate-N-acetylglucosamine-2'-epimerase activity; uridine diphospho-N-acetylglucosamine 2'-epimerase activity; uridine diphosphoacetylglucosamine 2'-epimerase activity
xref:
EC:5.1.3.14; MetaCyc:UDPGLCNACEPIM-RXN; RHEA:17213; Reactome:R-HSA-4088338 "Defective GNE does not hydrolyse UDP-GlcNAc"; reactome:R-HSA-4085021 "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP"
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Genes (1)
UDP-N-acetylglucosamine 2-epimerase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
enables
IDA
IEA
ISO
IBA
PMID:10334995
PMID:10497249
GO_REF:0000107
PMID:9305887
(PMID:14707127), (PMID:26980148), (PMID:2808337)
GO_REF:0000033
MGI:3713799 (PMID:10745088), (PMID:11929971), (PMID:17549255)
Ensembl
RGD
GO_Central
PMID:2808337
PMID:10745088
PMID:11929971
PMID:14707127
PMID:17549255
PMID:26980148
PMID:9305888
PMID:10334995
PMID:10497249
PMID:9305887
More...
GO_REF:0000033 GO_REF:0000107,
RGD:68786
,
RGD:401901215
,
RGD:401901233
,
RGD:401901241
NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
Term paths to the root
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Path 1
Term
Annotations
molecular_function
20633
catalytic activity
6032
isomerase activity
212
racemase and epimerase activity
17
racemase and epimerase activity, acting on carbohydrates and derivatives
10
UDP-N-acetylglucosamine 2-epimerase activity
1