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ONTOLOGY REPORT - ANNOTATIONS

Term:platelet-derived growth factor receptor activity
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Accession:GO:0005017 term browser browse the term
Definition:Combining with platelet-derived growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: PDGF receptor activity;   PDGF-activated receptor activity;   PDGFR activity;   platelet-derived growth factor-activated receptor activity


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platelet-derived growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRB platelet derived growth factor receptor beta enables ISO (PMID:26437238) RGD
MGI		 PMID:8318539 PMID:11903042 PMID:26437238 RGD:1581762 RGD:633648 NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,756...151,192,647 		JBrowse link
platelet-derived growth factor alpha-receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRA platelet derived growth factor receptor alpha enables ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central
InterPro
Ensembl		 PMID:2157969 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:729439 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,441 		JBrowse link
platelet-derived growth factor beta-receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFRB platelet derived growth factor receptor beta enables IEA
IBA		 Ensembl
InterPro
TreeGrafter
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,756...151,192,647 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18691
    catalytic activity 5667
      catalytic activity, acting on a protein 2329
        protein kinase activity 581
          transmembrane receptor protein kinase activity 79
            transmembrane receptor protein tyrosine kinase activity 61
              platelet-derived growth factor receptor activity 2
                platelet-derived growth factor alpha-receptor activity 1
                platelet-derived growth factor beta-receptor activity 1
Path 2
Term Annotations click to browse term
  molecular_function 18691
    catalytic activity 5667
      transferase activity 2373
        transferase activity, transferring phosphorus-containing groups 948
          kinase activity 801
            protein kinase activity 581
              protein tyrosine kinase activity 122
                transmembrane receptor protein tyrosine kinase activity 61
                  platelet-derived growth factor receptor activity 2
                    platelet-derived growth factor alpha-receptor activity 1
                    platelet-derived growth factor beta-receptor activity 1
paths to the root