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ONTOLOGY REPORT - ANNOTATIONS


Term:hepatocyte growth factor receptor activity
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Accession:GO:0005008 term browser browse the term
Definition:Combining with hepatocyte growth factor receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: HGF receptor activity;   HGF-activated receptor activity;   hepatocyte growth factor-activated receptor activity



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hepatocyte growth factor receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MET MET proto-oncogene, receptor tyrosine kinase enables ISO
IBA
IEA
RGD
GO_Central
TreeGrafter
PMID:18262389 GO_REF:0000033 GO_REF:0000118 RGD:2317458 NCBI chr18:29,426,044...29,541,526
Ensembl chr18:29,426,048...29,541,512
JBrowse link
G MST1R macrophage stimulating 1 receptor enables IEA TreeGrafter GO_REF:0000118 NCBI chr13:32,401,623...32,423,614
Ensembl chr13:32,409,555...32,421,920
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18691
    catalytic activity 5667
      catalytic activity, acting on a protein 2329
        protein kinase activity 581
          transmembrane receptor protein kinase activity 79
            transmembrane receptor protein tyrosine kinase activity 61
              hepatocyte growth factor receptor activity 2
Path 2
Term Annotations click to browse term
  molecular_function 18691
    catalytic activity 5667
      transferase activity 2373
        transferase activity, transferring phosphorus-containing groups 948
          kinase activity 801
            protein kinase activity 581
              protein tyrosine kinase activity 122
                transmembrane receptor protein tyrosine kinase activity 61
                  hepatocyte growth factor receptor activity 2
paths to the root