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ONTOLOGY REPORT - ANNOTATIONS

Term:proline-tRNA ligase activity
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Accession:GO:0004827 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
Synonyms:exact_synonym: prolyl-tRNA synthetase activity
 related_synonym: L-proline:tRNAPro ligase (AMP-forming);   proline translase activity;   prolinyl-tRNA ligase activity;   prolyl-s-RNA synthetase activity;   prolyl-transfer ribonucleate synthetase activity;   prolyl-transfer ribonucleic acid synthetase activity;   prolyl-transferRNA synthetase activity
 xref: EC:6.1.1.15;   MetaCyc:PROLINE--TRNA-LIGASE-RXN;   RHEA:14305;   reactome:R-HSA-379865 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate";   reactome:R-HSA-380198 "proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate"


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proline-tRNA ligase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 enables IEA InterPro
UniProt
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:195,537,319...195,618,257
Ensembl chr 1:200,575,259...200,656,197 		JBrowse link
G PARS2 prolyl-tRNA synthetase 2, mitochondrial enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000118 NCBI chr 1:54,032,594...54,040,274
Ensembl chr 1:55,622,726...55,624,750 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      ligase activity 167
        ligase activity, forming carbon-oxygen bonds 43
          aminoacyl-tRNA ligase activity 43
            proline-tRNA ligase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 17494
    catalytic activity 5388
      catalytic activity, acting on a nucleic acid 593
        catalytic activity, acting on RNA 366
          catalytic activity, acting on a tRNA 132
            aminoacyl-tRNA ligase activity 43
              proline-tRNA ligase activity 2
paths to the root