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ONTOLOGY REPORT - ANNOTATIONS

Term:Parkin-FBXW7-Cul1 ubiquitin ligase complex
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Accession:GO:1990452 term browser browse the term
Definition:A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.
Synonyms:exact_synonym: PARK2-FBXW7-Cul1 complex;   PRKN-FBXW7-Cul1 complex;   Parkin-FBXW7-Cul1 protein complex;   Parkin/Cul1/F-box protein complex
 narrow_synonym: Parkin-HSel-10-Cullin-1 complex


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Parkin-FBXW7-Cul1 ubiquitin ligase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cul1 cullin 1 part_of ISO UniProtKB:O60260 (PMID:12628165) RGD PMID:12628165 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 part_of ISO UniProtKB:O60260 (PMID:12628165) RGD PMID:12628165 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase part_of ISO
ISS
IEA		 UniProtKB:Q969H0 (PMID:12628165)
GO_REF:0000024
GO_REF:0000107		 RGD
ParkinsonsUK-UCL
Ensembl		 PMID:12628165 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6599
      intracellular protein-containing complex 931
        ubiquitin ligase complex 322
          Parkin-FBXW7-Cul1 ubiquitin ligase complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6599
      catalytic complex 1823
        transferase complex 880
          ubiquitin ligase complex 322
            Parkin-FBXW7-Cul1 ubiquitin ligase complex 3
paths to the root