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ONTOLOGY REPORT - ANNOTATIONS

Term:broken chromosome clustering
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Accession:GO:0141112 term browser browse the term
Definition:The process of bringing together chromosomes fragments resulting from DNA damage. Broken chromosome tethering during mitosis ensures clustered segregation of the fragments to a single daughter cell nucleus, facilitating re-ligation with limited chromosome scattering and loss and enhancing genome integrity.


show annotations for term's descendants           Sort by:
broken chromosome clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cip2a cellular inhibitor of PP2A involved_in ISO (PMID:37165191), (PMID:37316668) RGD PMID:37165191 PMID:37316668 NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:37165191), (PMID:37316668) RGD PMID:37165191 PMID:37316668 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20115
    response to stimulus 10590
      response to stress 4205
        cellular response to stress 2007
          DNA damage response 866
            broken chromosome clustering 2
Path 2
Term Annotations click to browse term
  biological_process 20115
    cellular process 18525
      cellular component organization or biogenesis 7044
        cellular component organization 6793
          organelle organization 3691
            chromosome organization 583
              broken chromosome clustering 2
paths to the root