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ONTOLOGY REPORT - ANNOTATIONS

Term:broken chromosome clustering
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Accession:GO:0141112 term browser browse the term
Definition:The process of bringing together chromosomes fragments resulting from DNA damage. Broken chromosome tethering during mitosis ensures clustered segregation of the fragments to a single daughter cell nucleus, facilitating re-ligation with limited chromosome scattering and loss and enhancing genome integrity.

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broken chromosome clustering term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cip2a cellular inhibitor of PP2A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:40,541,869...40,572,565 JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 involved_in ISO (PMID:37165191), (PMID:37316668) UniProt PMID:37165191 PMID:37316668 NCBI chrNW_004624730:9,916,717...9,994,666
Ensembl chrNW_004624730:9,914,140...9,994,775 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    response to stimulus 8161
      response to stress 3540
        cellular response to stress 1814
          DNA damage response 780
            broken chromosome clustering 2
Path 2
Term Annotations click to browse term
  biological_process 15093
    cellular process 14237
      cellular component organization or biogenesis 6217
        cellular component organization 6020
          organelle organization 3386
            chromosome organization 520
              broken chromosome clustering 2
paths to the root