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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K4 monomethyltransferase activity
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Accession:GO:0140945 term browser browse the term
Definition:Catalysis of the reaction: L-lysyl4-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl4-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 4 of histone H3, producing histone H3K4me.
Synonyms:exact_synonym: histone H3K4 monomethylase activity;   histone lysine N-monomethyltransferase activity (H3-K4 specific)
 broad_synonym: histone H4-K4 methylation;   histone H4K4 methylation
 xref: EC:2.1.1.364;   RHEA:60264



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histone H3K4 monomethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmt2a lysine methyltransferase 2A enables IEA GO_REF:0000116 RHEA GO_REF:0000116 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181
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G Setd7 SET domain containing 7, histone lysine methyltransferase enables IEA GO_REF:0000003
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000003 NCBI chr 2:135,562,683...135,605,468
Ensembl chr 2:135,562,683...135,605,468
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Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      catalytic activity, acting on a protein 2445
        protein methyltransferase activity 106
          protein-lysine N-methyltransferase activity 67
            histone H3K4 methyltransferase activity 17
              histone H3K4 monomethyltransferase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      transferase activity 2398
        transferase activity, transferring one-carbon groups 218
          methyltransferase activity 208
            S-adenosylmethionine-dependent methyltransferase activity 168
              lysine N-methyltransferase activity 67
                protein-lysine N-methyltransferase activity 67
                  histone H3K4 methyltransferase activity 17
                    histone H3K4 monomethyltransferase activity 2
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